Sökning: "B-cells"

Visar resultat 1 - 5 av 503 avhandlingar innehållade ordet B-cells.

  1. 1. B cells in Autoimmunity : Studies of Complement Receptor 1 & 2 and FcγRIIb in Autoimmune Arthritis

    Författare :Kajsa Prokopec; Sandra Kleinau; Anna Erdei; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B cells; complement receptors; fc gamma receptor IIb; autoimmune arthritis; rheumatoid arthritis; Immunology; Immunologi;

    Sammanfattning : B cells are normally regulated to prevent activation against self-proteins through tolerance mechanisms.  However, occasionally there is a break in tolerance and B cells can become self-reactive, which might lead to the development of autoimmune disease. LÄS MER

  2. 2. IL-25 and B cells in atherosclerosis

    Författare :Polyxeni Mantani; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-25; B cells; ILC2s; IL-5; anti-PC IgM; atherosclerosis; stroke; cardiovascular events;

    Sammanfattning : Atherosclerosis is a chronic inflammatory disease of medium and large vessels of the body which is mainly characterized by the formation of lipid rich plaques within the arterial tissue. It is the most common cause of cardiovascular disease leading to clinical manifestations of coronary artery and cerebrovascular disease. LÄS MER

  3. 3. The role of B cells in rheumatoid arthritis

    Författare :Maria Rehnberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B cells; Rheumatoid arthritis; B cell depletion therapy;

    Sammanfattning : It has been known for a long time that B cells play a role in rheumatoid arthritis (RA). By production of autoantibodies, presentation of auto-antigens and by producing cytokines B cells may contribute to the pathogenesis of RA. In recent years it has been shown that anti-B cell therapy is a powerful tool in the treatment of RA. LÄS MER

  4. 4. Life and death of human B cells in health and disease

    Författare :Andy Dernstedt; Mattias N. E. Forsell; Clas Ahlm; Jonas Klingström; Mats Bemark; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; b cells; antibody; hantavirus; germinal centre; phagocytosis; selection; DAF; vaccination; rituximab;

    Sammanfattning : B cells provide one of the key mechanisms of immunological memory, which is theproduction of neutralising antibodies. How B cells respond to infections and vaccinationgives clues to how the development of the immunological memory is facilitated, and canthus lead to a deeper understanding of why the immune system sometimesmalfunctions. LÄS MER

  5. 5. Activation of human B cells with the Moraxella catarrhalis IgD-binding protein MID

    Författare :Radinka Hadzic; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mikrobiologi; bakteriologi; virology; mycology; bacteriology; AAT; Microbiology; tonsils; CD19; CD21; MID; B cells; serology; virologi; mykologi; Immunology; transplantation; Immunologi; serologi; Moraxella catarrhalis;

    Sammanfattning : Moraxella catarrhalis is a respiratory tract pathogen that causes significant health problems, including acute otitis media in children, lower respiratory tract infections in adults and the elderly and sinusitis in both children and adults. The interest in M. LÄS MER