Sökning: "Thomas Walz"
Hittade 5 avhandlingar innehållade orden Thomas Walz.
1. Transforming growth factor a in human hematopoietic cells
Sammanfattning : TGF-a, transforming growth factor a, is a potent growth factor belonging to the family of EGF (epidermal growth factor) -related proteins. Binding to the same receptor as EGF it has a ubiquitous repertoire of target cells, including, mesenchymal, epithelial and neuronal cells. LÄS MER
2. Studies on the effect of ErbB tyrosine kinase inhibitors on malignant melanoma growth and survival in vitro
Sammanfattning : Malignant melanoma has one of the fastest increasing incidences among the different types of cancerin the Western world. This raise can partly be ascribed to the change in sun habits that has takenplace during the last decades, since the major external risk factor for melanoma is exposure toultraviolet radiation. LÄS MER
3. Studies of transforming growth factor alpha in normal and abnormal growth
Sammanfattning : Regulation of growth is of fundamental importance for development of the organism and to maintain health. The induction of cell proliferation and matrix production are influenced by several different signaling systems, most importantly by growth factors. LÄS MER
4. Experimental studies on ErbB targeted therapy in malignant melanoma
Sammanfattning : Malignant melanoma has one of the fastest increasing incidences among the different types of cancer in the Western world. This raise can partly be ascribed to the change in sun habits that has taken place during the last decades, since the major external risk factor for melanoma is exposure to ultraviolet radiation. LÄS MER
5. Canertinib-induced leukemia cell death signaling : effects of a pan-ERBB inhibitor
Sammanfattning : Acute myelogenous leukemia (AML) is the most common acute leukemia affecting adults, the second most frequent leukemia in children, and remains one of the most difficult to cure. Despite a substantial progress in understanding the pathogenesis of AML, general and rather unspecific cytostatic drugs such as cytarabine and anthracyclins still make up the cornerstones of therapy. LÄS MER