Sökning: "target fragmentation"

Visar resultat 21 - 25 av 38 avhandlingar innehållade orden target fragmentation.

1. 21. Production of high quality 11C beams for radiation treatment and accurate PET-CT dose delivery verification

   Författare :Marta Lazzeroni; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Radiation therapy with external beams of positron emitter light ions offers the optimal solution for simultaneously treating and in vivo monitoring the delivery of the dose in 3D with Positron Emission Tomography (PET) or PET-Computed Tomography (CT) imaging. Specifically, positron emitter light ion beams merge the main distinctive advantages of light ion therapy, namely a high conformal and biological effective dose delivery to the tumor, an optimal penumbra, and sparing of the surrounding normal tissues, with the advantage of a high β+-activity signal mainly produced directly by the beam itself, and therefore not primarily dependent on the specific stoichiometry of the body tissues. LÄS MER

3. 22. Single-photon multiple ionisation of atoms and molecules investigated by coincidence spectroscopy : Site-specific effects in acetaldehyde and carbon dioxide

   Författare :Sergey Zagorodskikh; Raimund Feifel; Vitali Zhaunerchyk; Melanie Mucke; Maria Novella Piancastelli; Tom Field; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; acetaldehyde; carbon dioxide; xenon; electron correlation; double ionisation; triple ionisation; core-valence ionisation; site-specific Auger decay; multiple Auger decay; branching ratios; site-specific photodissociation; molecular rearrangement; time-of-flight multi-electron-ion coincidence spectroscopy; synchrotron radiation; Physics with spec. in Atomic; Molecular and Condensed Matter Physics; Fysik med inriktning mot atom- molekyl- och kondenserande materiens fysik;

   Sammanfattning : In this thesis, multiple ionisation processes of free atoms and molecules upon single photon absorption are studied by means of a versatile multi-electron-ion coincidence spectroscopy method based on a magnetic bottle, primarily in combination with synchrotron radiation. The latter offered the possibility to access not only valence but also core levels, revealing processes, which promote the target systems into different charge states. LÄS MER

4. 23. Isotope-Selective Spectroscopy: Fast Timing R&D and fp-Shell Mirror Isomers

   Författare :Robert Hoischen; Kärnfysik; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mirror isomer; time of flight; plastic scintillator; fast timing; time resolution; Fysicumarkivet A:2011:Hoischen;

   Sammanfattning : This thesis highlights the research and development of a new plastic-scintillator detector for time-of-flight measurements in relativistic heavy-ion beam experiments. The detector makes possible the identification of different ion species on flight distances as short as a few meters. LÄS MER

5. 24. Neurotoxicity of methylmercury : analysis of molecular mechanisms and behavioral alterations

   Författare :Elisabetta Daré; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Apoptosis; oxidative stress; neurons; glia; rats; dopamine; locomotion; learning and memory; environmental pollutants;

   Sammanfattning : MethyImercury (MeHg) is a global pollutant that is toxic for the nervous system, especially during development. Contaminated fish is the main route of human exposure. Recent studies have indicated that neurological alterations in humans may occur even after exposure to fairly low levels of MeHg. LÄS MER

7. 25. Analysis of drugs and proteins in biological matrices, using different types of sample preparations and mass spectrometry

   Författare :Aljona Saleh; Ingrid Granelli; Jonas Bergquist; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioanalysis; drugs; proteins; liquid chromatography; two-dimensional liquid chromatography; mass spectrometry; Analytical Chemistry; analytisk kemi;

   Sammanfattning : This thesis describes bioanalysis of small and large molecules in biological matrices and includes screening of illegal drugs in urine with high resolution mass spectrometer, bioanalysis of MTH1 inhibitors in mice plasma and quantification of proteins in plasma and cell lysates.Screening of illegal drugs was based on high resolving power mass spectrometer (QTOF) and the results were compared to immunoassays. LÄS MER