Sökning: "Aljona Saleh"

Hittade 1 avhandling innehållade orden Aljona Saleh.

1. 1. Analysis of drugs and proteins in biological matrices, using different types of sample preparations and mass spectrometry

   Författare :Aljona Saleh; Ingrid Granelli; Jonas Bergquist; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioanalysis; drugs; proteins; liquid chromatography; two-dimensional liquid chromatography; mass spectrometry; Analytical Chemistry; analytisk kemi;

   Sammanfattning : This thesis describes bioanalysis of small and large molecules in biological matrices and includes screening of illegal drugs in urine with high resolution mass spectrometer, bioanalysis of MTH1 inhibitors in mice plasma and quantification of proteins in plasma and cell lysates.Screening of illegal drugs was based on high resolving power mass spectrometer (QTOF) and the results were compared to immunoassays. LÄS MER