Sökning: "subcortical ischemia"

Hittade 5 avhandlingar innehållade orden subcortical ischemia.

  1. 1. The search for reversibility of Idiopathic normal pressure hydrocephalus : Aspects on intracranial pressure measurments and CSF volume alteration

    Författare :Niklas Lenfeldt; Jan Malm; Anders Eklund; Katrine Riklund-Åhlström; John D. Pickard; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Idiopathic normal pressure hydrocephalus; intracranial pressure; subcortical ischemia; neuronal integrity; cortical activation.; infusion test; cerebrospinal fluid dynamics; outflow resistance; compliance; elastance; proton spectroscopy; functional MRI; external lumbar drainage; Neurology; Neurologi;

    Sammanfattning : BACKGROUND: Idiopathic normal pressure hydrocephalus (INPH) is still a syndrome generating more questions than answers. Today, research focuses mainly on two areas: understanding the pathophysiology – especially how the malfunctioning CSF system affects the brain parenchyma – and finding better methods to select patients benefiting from a shunt operation. LÄS MER

  3. 2. Experimental Stroke and Neurotrophins: Regulation, function and gene transfer of neurotrophins in rat and mouse models of focal cerebral ischemia

    Författare :Gunnar Andsberg; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsychology; Neurology; animal behaviour; striatum; stereology; immunohistochemistry; focal cerebral ischemia; nerve growth factors; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : Stroke caused by focal cerebral ischemia is a major cause of death and neurological disability in humans. The forebrain region most commonly affected by ischemic incidents is that supplied by the middle cerebral artery. LÄS MER

  4. 3. Recovery from focal brain ischemia induced by extradural compression in diabetic and non-diabetic rats

    Författare :Tiago J T Prazeres Moreira; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Focal ischemia; locomotor activity; lever-press task; neurodegeneration; hyperglycemia; Goto-Kakizaki rats; Fluoro-Jade; heme-oxygenase; astrocytes; microglia.;

    Sammanfattning : Cerebrovascular disease and head trauma are among the leading causes of death and disability. In addition to severe motor disturbances, ischemia resulting from stroke or traumatic brain injury (TBI) can cause mild to severe cognitive deficits. LÄS MER

  5. 4. Pathophysiology of intrauterine asphyxia

    Författare :Anna-Karin Welin; Göteborgs universitet; []
    Nyckelord :asphyxia; ECG; endotoxemia; fetal sheep; inflammation; melatonin; periventricular leukomalacia; preterm;

    Sammanfattning : Background: The premature infant is at increased risk of cerebral white matter damage, oftenreferred to as periventricular leucomalacia, PVL, which is associated with later developmentof cerebral palsy and cognitive impairment. The etiology of PVL remains unclear, but ischemia-reperfusion followed by generation of free radicals and intrauterine infections havebeen suggested to play an important role. LÄS MER

  7. 5. On the pathophysiology of idiopathic adult hydrosephalus syndrome : energy metabolism, protein patterns, and intracranial pressure

    Författare :Aina Ågren Wilsson; Per Enblad; Umeå universitet; []
    Nyckelord :hydrocephalus; biochemical markers; microdialysis; cerebrospinal fluid; B waves; brain tissue oxygen tension; Neurology; neurologi;

    Sammanfattning : The symptoms in Idiopathic Adult Hydrocephalus Syndrome (IAHS) – gait disturbance, incontinence, and cognitive deficit – correlate anatomically to neuronal dysfunction in periventricular white matter. The pathophysiology is considered to include a cerebrospinal fluid (CSF) hydrodynamic disturbance, including pressure oscillations (“B waves”), in combination with cerebrovascular disease. LÄS MER