Sökning: "scintigraphic imaging"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden scintigraphic imaging.

1. 1. Corrections for improved quantitative accuracy in SPECT and planar scintigraphic imaging

   Författare :Anne Larsson; Lennart Johansson; Katrine Åhlström Riklund; Bertil Axelsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Quantitative SPECT; scintigraphic imaging; attenuation correction; scatter correction; collimator-detector response; septal penetration; background correction; Monte Carlo simulation; Radiological physics; Radiofysik;

   Sammanfattning : A quantitative evaluation of single photon emission computed tomography (SPECT) and planar scintigraphic imaging may be valuable for both diagnostic and therapeutic purposes. For an accurate quantification it is usually necessary to correct for attenuation and scatter and in some cases also for septal penetration. LÄS MER

3. 2. Superparamagnetic iron oxide nanoparticles (SPIONs) as a multimodality imaging probe for sentinel nodes : Design and Preclinical Evaluation

   Författare :Renata Madru; Lund Medicinsk strålningsfysik; []
   Nyckelord :iron oxide; nanoparticles; SPIONs; PET-MRI; SPECT-MRI; SPECT-MRI- optical imaging; sentinel lymph node; SNL;

   Sammanfattning : Breast cancer and malignant melanoma disseminate through the lymphatic system and the first metastases arise in one or two regional, sentinel lymph nodes (SLNs) draining the primary tumour site. Therefore, identification and characterization of the SLNs is of major importance for cancer staging and for choice of therapy in patients. LÄS MER

4. 3. Interventions for portal hypertension in patients with portal vein occlusion and possible effects of a stent-graft on hepatic circulation

   Författare :Inger Keussen; Malmö Diagnostisk radiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; recanalization; TIPS; hepatic vein occlusion; children; Key words: portal vein occlusion; scintigraphy; stent; portal hypertension;

   Sammanfattning : Symptomatic portal hypertension (PH), is often treated by transjugular intrahepatic portosystemic shunt (TIPS). Patients with PH, caused by prehepatic portal vein occlusion, require recanalization with stent or stent-graft often followed by additional TIPS. LÄS MER

5. 4. Diagnosis and evaluation of therapeutic response of bone metastases

   Författare :Ipek Çiray; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Bone metastases; breast neoplasm; MR imaging; CT; diagnosis; therapy evaluation; Onkologi; Oncology; Onkologi; diagnostisk radiologi; Diagnostic Radiology;

   Sammanfattning : The aim of this study was to investigate different aspects of different imaging modalities in the diagnosis of bone metastases and in the assessment of their response to therapy. The role of CT, with and without clinical information, was investigated as compared to CT-guided bone biopsy in the evaluation of suspected bone metastases. LÄS MER

7. 5. Deposition and absorption of inhaled drugs

   Författare :Eva Bondesson; Malmö Klinisk fysiologi och nuklearmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tomografi; radiologi; Klinisk fysiologi; medical instrumentation; tomography; radiology; Clinical physics; technetium-99m; radionuclide imaging; radioactive aerosol; powder inhaler; pharmacokinetics; mucociliary clearance; lung deposition; gamma scintigraphy; inhalation; deposition modelling; drug absorption; absorption enhancer; aerosol; medicinsk instrumentering; Physiology; Fysiologi;

   Sammanfattning : Main objectives of this thesis were to evaluate a gamma scintigraphic method used to quantify drug aerosol deposition in the lung, to investigate the influence of two aerosol inhalation parameters on the distribution of inhaled dry powder within the airways, to assess pulmonary absorption kinetics and bioavailability of an inhaled hydrophilic solute in relation to site of deposition, and to assess the influence of a surface active agent (sodium taurocholate, a bile salt) on the deposition and absorption of an inhaled hydrophilic solute. Repeated planar gamma scintigraphy was found to provide the same information on total pulmonary drug deposition as an independent method that involved assessments of urinary drug recovery after blockage of gastrointestinal drug absorption when all of the critical parts of the methodological procedures were accurately and meticulously executed. LÄS MER