Sökning: "retinal development"

Visar resultat 26 - 30 av 81 avhandlingar innehållade orden retinal development.

  1. 26. Pre-, peri- and postnatal influences on ophthalmologic outcome - a study on children born after intracytoplasmic sperm injection (ICSI) and children born preterm

    Författare :Margareta Hök Wikstrand; Göteborgs universitet; []
    Nyckelord :visual function; intracytoplasmic sperm injection; preterm birth; growth; insulin-like growth factor 1; postnatal development; ocular fundus morphology;

    Sammanfattning : The aims of the present study were to investigate the effects of prenatal factors in children born after intracytoplasmic sperm injection (ICSI) and peri- and postnatal factors in children born preterm on visual function and ocular fundus morphology at school age. In the children born preterm the ophthalmologic outcomes, including optic nerve morphology were analysed in relation to gestational age (GA), birth weight (BW) standard deviation score (SDS), serum levels of insulin-like growth factor I (IGF-I), weight at week 32 (SDS), and weight, length and head circumference (SDS) at school age. LÄS MER

  3. 27. Central retinal vein occlusion: Cetrain risk factors, electroretinography and an experimental treatment model

    Författare :Jörgen Larsson; Lund Oftalmologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; flicker; ERG; electroretinography; fluorescein angiography; rubeosis; CRVO; central retianl vein occlusion; ultrasound; streptokinase; experimental; Ophtalmology; Oftalmologi;

    Sammanfattning : The presence of activated protein C resistance, plasma hyperhomocysteinemia and the MTHFR C677T mutation in patients with central retinal vein occlusion were investigated and compared to a control group. Activated protein C resistance was overrepresented in the group of patients less than 50 years of age whereas this was not the case in patients more than 50 years of age. LÄS MER

  4. 28. Experimental transplantation of retinal and iris pigment epithelial cells into the subretinal space

    Författare :Sven Crafoord; Jan Ulrik Prause; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : A dysfunction of the retinal pigment epithelium (RPE) is the main cause for the development of age-related macular degeneration (ARMD) and visual loss in elderly people. For about 10 years experimental and clinical attempts to transplant RPE cells have been performed. LÄS MER

  5. 29. Role of extracellular retention of platelet-derived growth factor-B. Functions in development and disease

    Författare :Per Lindblom; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGF; pericyte; cancer; fibrosis; ECM; HSPG; cell retention; endothelial;

    Sammanfattning : During development, the cell secretes growth and differentiation factors (GDFs) to the surrounding microenvironment. These factors are often key regulators of organogenesis and embryogenesis. Several GDFs carry sequences that mediate specific interaction with molecules of the extracellular matrix (ECM) that surrounds the cell. LÄS MER

  7. 30. Scalable, safe and GMP-compatible production of embryonic stem cell derived retinal pigment epithelial cells

    Författare :Sara Padrell Sánchez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Regenerative medicine is an exponentially growing field that aims to regenerate a lost function, cell type or tissue due to damage, ageing or disease. Currently, more than 30,000 gene- and cell-based therapies have been or are being tested in clinical trials. LÄS MER