Sökning: "pattern discovery"

Visar resultat 6 - 10 av 66 avhandlingar innehållade orden pattern discovery.

1. 6. Som en vit ros och så där... : 52 patienters upplevelser av sin cancersjukdom och vården omkring den

   Författare :Gunnel Drugge; Umeå universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; cancer; psychosocial; crisis; personal discovery; diagnosis; cancer image; check-ups; continuity among doctors; day to day living; way of life; method for psychosocial care; Omvårdnad psykologiska aspekter;

   Sammanfattning : The study describes 52 patients' experiences and feelings towards theirillness and the care received in connection with it. The main purpose ofthe study is to gather knowledge on cancer patients' need of psychosocialcare and from this insight draw up a proposition for a clinically usefulmethod for psychosocial care. LÄS MER

3. 7. 3D Printed scaffolds as cancer microenvironment medels for drug discovery

   Författare :Jennifer Rosendahl; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 3D Printing; Breast cancer; Biomaterials; Drug development;

   Sammanfattning : Cancer is one of the most common diseases in the modern world and major efforts are made globally to develop new diagnostics and treatments. It originates from a cell which, at some point, has begun to divide and grow uncontrollably. The most common type is breast cancer, and like all other cancers there is a need of more efficient drug therapies. LÄS MER

4. 8. Development and application of new methods for anticancer drug discovery and early evaluation

   Författare :Sumeer Dhar; Uppsala universitet; []
   Nyckelord :Medical sciences; Drug development; tumor cell lines; cytotoxic drugs; neural network; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; klinisk farmakologi; Clinical Pharmacology;

   Sammanfattning : A non-clonogenic assay using the redox dye Alamar Blue and primary human tumor cells (PHTC) from patients and human tumor cell lines (HTCL) was established for rapid screening and evaluation of anticancer drugs. PHTC cultures from chronic lymphocytic leukemia (CLL) and ovarian carcinoma (Ovca) were compared with renal carcinoma (ACHN) and lymphocytic (CCRF-CEM) HTLCs in response to 63 toxic or non-toxic compounds. LÄS MER

5. 9. The role of RNA-binding motif 3 in epithelial ovarian cancer: A biomarker discovery approach

   Författare :Åsa Ehlén; Malmö Patologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA integrity checkpoint; cisplatin treatment; prognostic predictive marker; RBM3; epithelial ovarian cancer; Chk1; Chk2; MCM3;

   Sammanfattning : Epithelial ovarian cancer (EOC) is the most lethal of all gynaecological malignancies and there is an urgent need to develop new prognostic and treatment predictive biomarkers for a more efficient therapy. The discovery of the RNA-binding motif protein 3 (RBM3) as a putative cancer biomarker was based on its differential expression in various cancer forms in the Human Protein Atlas (HPA). LÄS MER

7. 10. Discovery of a novel pathway for an SLE-related disease complex in the canine breed Nova Scotia duck tolling retriever

   Författare :Maria Wilbe; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : The dog is an excellent model to study inherited complex diseases, due to its unique population history and haplotype structure. In this thesis, dogs from the breed Nova Scotia duck tolling retriever (NSDTR) have been used as a model for defining the genetic factors controlling a systemic lupus erythematosus (SLE)-related disorder called immune-mediated rheumatic disease (IMRD) and a steroid responsive meningitis-arteritis (SRMA). LÄS MER