Sökning: "epithelial ovarian cancer"

Visar resultat 1 - 5 av 53 avhandlingar innehållade orden epithelial ovarian cancer.

1. 1. Impact of pregnancies on ovarian cancer : Risk, prognosis and tumor biology

   Författare :Camilla Sköld; Ingrid Glimelius; Karin Stålberg; Anthoula Koliadi; Gunilla Enblad; Annika Idahl; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epithelial ovarian cancer; non-epithelial ovarian cancer; reproductive history; parity; risk factor; survival; progesterone receptor;

   Sammanfattning : Ovarian cancer is the most lethal gynecological malignancy. The etiology is complex and not fully understood, partly since ovarian cancer is not one distinct disease, but rather several histologically and clinically different subtypes. LÄS MER

3. 2. Mechanisms for immune escape in epithelial ovarian cancer

   Författare :Pernilla Israelsson; Ulrika Ottander; Lucia Mincheva-Nilsson; Eva Lundin; Ivan Nagaev; Karin Sundfeldt; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human; ovarian cancer; high-grade serous cancer; EOC; HGSC; HGSOC; tumor microenvironment; immune escape; immune suppression; cytokines; exosomes; NKG2D; MICA B; ULBP1-3; DNAM-1; surgery; obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : Tumors develop mechanisms to subvert the immune system, constituting immune escape. Epithelial ovarian cancer (EOC), the deadliest of all gynecological malignancies, uses a variety of mechanisms to undermine immune surveillance, aiding its establishment and metastatic spreading. LÄS MER

4. 3. Ovarian cancer : Treatment results, prognostic factors, and tumor marker surveillance

   Författare :Thomas Högberg; Claes Tropé; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : The total population-based material of 426 ovarian malignancies in the Southeast Health Care Region of Sweden during 1984-1987 was surveyed. It seems that with a program of cytoreductive surgery followed by a cisplatinum chemotherapy combination in the metastasizing cases the overall survival figures have improved. LÄS MER

5. 4. Intrinsic subtypes and prognostic implications in epithelial ovarian cancer

   Författare :Jenny-Maria Jönsson; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian cancer; gene expression profiling; Lynch syndrome; targeted deep sequencing; chromatin remodeling; molecular subtypes; endocrine receptors; prognostic factors; tumor heterogeneity;

   Sammanfattning : Ovarian cancer is the seventh most common cancer in women globally, with approximately 240,000 new cases annually. Although a rare disease, it is the most lethal gynecologic malignancy. Unspecific symptoms result in late diagnosis and a generally poor prognosis. LÄS MER

7. 5. Effects of Oral Contraceptives on Endogenous Hormones, Body Constitution, and Breast Epithelium in Healthy, Young Women

   Författare :Helena Jernström; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytology; ovarian; breast cancer; proliferation; breast size; progesterone; estradiol; testosterone; luteinizing hormone; follicle stimulating hormone; sexual hormone binding globulin; insulin-like growth-factor-1; prolactin; Oral contraceptives; nulliparous women; oncology; cancerology; Cytologi; onkologi; cancer; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

   Sammanfattning : This thesis concerns the effects of low-dose oral contraceptives (OCs) on endogenous hormones, insulin-like growth-factor-1 (IGF-1), sexual hormone binding globulin (SHBG), and body constitution in two groups of healthy women aged 19­25 who had never been pregnant. Prolactin concentrations were elevated in a subgroup of present and former users. LÄS MER