Hittade 4 avhandlingar innehållade ordet MCM3.
Sammanfattning : Epithelial ovarian cancer (EOC) is the most lethal of all gynaecological malignancies and there is an urgent need to develop new prognostic and treatment predictive biomarkers for a more efficient therapy. The discovery of the RNA-binding motif protein 3 (RBM3) as a putative cancer biomarker was based on its differential expression in various cancer forms in the Human Protein Atlas (HPA). LÄS MER
Sammanfattning : Epithelial ovarian cancer (EOC) is the most lethal malignancy of the female reproductive tract. Due to vague symptomatology, the majority of EOC patients are diagnosed in advanced clinical stages with poor survival rates, despite improvements in surgical techniques and the advent of targeted therapeutics. LÄS MER
Sammanfattning : Nuclear receptors are a family of transcription factors involved in many biological processes. They represent key potentials as therapeutic targets for several clinical conditions such as diabetes, obesity, cardiovascular disease and cancer, because their activity is modulated by small molecules. LÄS MER
4. Mammalian cell cycle regulation : characterisation of three genes expressed in proliferating cells
Sammanfattning : MAMMALIAN CELL CYCLE REGULATION: CHARACTERISATION OF THREE GENES EXPRESSED IN PROLIFERATING CELLS Maria Starborg Laboratory of Moleeular Genetics, Department of Cell and Moleeular Biology Karolinska Institutet, S-171 77 Stockholm Proliferating cells undergo different phases in their life cycle. During interphase thecells grow and duplicate their DNA content, followed by a cell division phase, mitosis,which results in two daughter cells. LÄS MER