Sökning: "neuropathic"

Visar resultat 11 - 15 av 98 avhandlingar innehållade ordet neuropathic.

  1. 11. Advances for Biomarker Discovery in Neuroproteomics using Mass Spectrometry : From Method Development to Clinical Application

    Författare :Marcus O.D. Sjödin; Magnus Wetterhall; Jonas Bergquist; Dominic M. Desiderio; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mass Spectrometry; Biomarker; Proteomics; Central Nervous System; Cerebrospinal Fluid; Traumatic Brain Injury; Cloud-Point Extraction; Neuroproteomics; Relative Quantification; Spinal Cord Stimulation; Neuropathic Pain; Analytical Chemistry; Analytisk kemi;

    Sammanfattning : Proteins offer a prominent group of compounds which may be ubiquitously affected in disease and used as biomarkers for early diagnosis, assessing treatment or drug development. Clinical proteomics aim to screen for protein biomarkers by a comprehensive analysis of all proteins expressed in a biological matrix during a certain pathology. LÄS MER

  2. 12. Chronic intraoral pain - assessment of diagnostic methods and prognosis

    Författare :Maria Pigg; Malmö högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuropathic pain; Orofacial pain; Trigeminal pain; Clinical studies; Prognosis; Diagnostic methods; Quantitative sensory testing; QST; Chronic pain; Endodontics;

    Sammanfattning : The overall goal of this thesis was to broaden our knowledge of chronic intraoral pain. The research questions were:•What methods can be used to differentiate inflammatory, odontogenic tooth pain from pain that presents as toothache but is non-odontogenic in origin?•What is the prognosis of chronic tooth pain of non-odontogenic origin, and which factors affect the prognosis?Atypical odontalgia (AO) is a relatively rare but severe and chronic pain condition affecting the dentoalveolar region. LÄS MER

  3. 13. Living with Long-Term Pain after a Stroke

    Författare :Marita Widar; Gerd Ahlström; Anna-Christina Ek; Fannie Gaston-Johansson; Linköpings universitet; []
    Nyckelord :stroke; central pain; chronic pain; neuropathic pain; nociceptive pain; shoulder; pain; tension-type headache; pain assessment; disability; activities of daily living; coping; health-related quality of life; mood; caring; MEDICINE; MEDICIN;

    Sammanfattning : The general aim of this thesis was to classify and describe long-term pain two years after a stroke and to describe the experiences of pain, and the consequences it has on the persons’ lives. The studies were conducted from a multidimensional perspective on pain, combining quantitative and qualitative methods. LÄS MER

  4. 14. Neuropathic pain : somatosensory functions related to spontaneous ongoing pain, mechanical allodynia and pain relief

    Författare :Åsa Landerholm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Peripheral neuropathic pain; Central post stroke pain; Dynamic mechanical allodynia; Static mechanical allodynia; Dysesthesia; Quantitative sensory testing; Spinal cord stimulation.;

    Sammanfattning : Introduction and aim: Patients with neuropathic pain suffer from spontaneous ongoing pain and from abnormal stimulus-evoked pain, e.g., allodynia. LÄS MER

  5. 15. Behavioural and neurochemical effects and changes in gene expression in inflammatory and neuropathic pain

    Författare :Eva Schött; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Inflammatory pain; neuropathic pain; pain-related behaviour; weight bearing; preemptive analgesia; immediate early genes; substance P; dynorphin; cholecystokinin; microdialysis;

    Sammanfattning : Chronic pain is a common clinical problem, which causes great suffering, and there is a great need for better analgesic drugs and strategies to counteract the transition of acute pain into chronic pain states. In studies of neurochemical mechanisms in animal models of chronic pain it is important to study also the development of spontaneous pain-related behaviour and sensory abnormalities (i. LÄS MER