Sökning: "neuropathic"

Visar resultat 21 - 25 av 98 avhandlingar innehållade ordet neuropathic.

  1. 21. Bioelectronic Devices for Targeted Drug Delivery and Monitoring of Microbial Electrogenesis

    Författare :Arghyamalya Roy; Daniel T Simon; Klas Tybrandt; Christopher Proctor; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Electrophoresis; Extracellular Electron Transfer EET ; Ion Exchange Membranes IEM ; Drug Delivery; Bupivacaine; Chronic Neuropathic Pain; Microfabrication; Inkjet Printing; Organic Electrochemical Transistor OECT ; Fumarate; Shewanella oneidensis; Dorsal Root Ganglia DRG ; Organic Electronic Ion Pump OEIP ;

    Sammanfattning : Despite a range of pain therapies available in the market, 70% of patients report so-called “breakthrough pain”. Coupled with global issues like opioid crisis, there is a clear need for advanced therapies and technologies for pain management. LÄS MER

  3. 22. Heritability and sex differences in experimental neuropathic pain with special emphasis on the role of the major histocompatibility complex

    Författare :Cecilia Dominguez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neuropathic pain caused by injury to the nervous system is a difficult clinical problem and a large proportion of patients experience no or only partial relief from existing treatments. Pain sensitivity and the development of neuropathic pain are complex biological and physiological entities that are known to be affected by genetics and sex. LÄS MER

  4. 23. On the function endogenous pain controlling systems in healthy subjects and patients with peripheral or central neuropathic pain

    Författare :Birgitta Tuveson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Painful peripheral neuropathy; Central post-stroke pain; Dynamic mechanical allodynia; Endogenous pain modulation; Heterotopic noxious conditioning stimulation; Quantitative sensory testing; Ondansetron;

    Sammanfattning : Introduction and aim: Activity in the nociceptive system is modulated by descending inhibitory and facilitatory supraspinal endogenous control. Altered balance between inhibition and facilitation has been suggested to at least partly explain the maintenance of some persistent pain conditions. LÄS MER

  5. 24. Neuropathic pain in an elderly population of an urban area of Iran with a special focus on carpal tunnel syndrome : epidemiological aspects, clinical characteristics, and non-surgical therapy

    Författare :Reza Salman Roghani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: People are getting older, and aging problems and disorders are increasing fast. Knowing the rates, causes, symptomatology, treatment, relief, and prognosis of associated disorders can help and facilitate the elderly, their families, primary health care providers, and health policymakers. LÄS MER

  7. 25. Genetic differences in neuropathy and opioid responses in rats

    Författare :Aleksandra Bulka; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Allodynia; genetic difference; neuropathic pain; NMDA-receptor; opioids; rat strains; pharmacokinetics; tolerance.;

    Sammanfattning : The studies examined mechanisms and treatments of experimental neuropathic pain with particular emphasis on the differences between rat strains and sub-strains in basal nociceptive sensitivity, development of neuropathic behaviors and sensitivity to opioid analgesia. In order to study the mechanisms that mediate mechanical allodynia (touch-evoked pain) following ischemic nerve injury to the sciatic nerve in rats, the myelinated primary afferents have been examined in the injured and intact nerves. LÄS MER