Sökning: "pain-related behaviour"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden pain-related behaviour.

1. 1. Interactions with pain-related systems - Towards new electrical treatments for chronic pain

   Författare :Matilde Forni; NanoLund: Centre for Nanoscience; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; High definition brain stimulation; Periaqueductal gray matter; Pain systems; Pain models;

   Sammanfattning : Background. Persistent intolerable pain is still an unsolved issue with a huge socioeconomic impact. To develop appropriate treatments, it is crucial to understand the complex mechanisms underlying pain and how they change during sustained pain stimuli or during pathological conditions. LÄS MER

3. 2. Behavioural and neurochemical effects and changes in gene expression in inflammatory and neuropathic pain

   Författare :Eva Schött; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Inflammatory pain; neuropathic pain; pain-related behaviour; weight bearing; preemptive analgesia; immediate early genes; substance P; dynorphin; cholecystokinin; microdialysis;

   Sammanfattning : Chronic pain is a common clinical problem, which causes great suffering, and there is a great need for better analgesic drugs and strategies to counteract the transition of acute pain into chronic pain states. In studies of neurochemical mechanisms in animal models of chronic pain it is important to study also the development of spontaneous pain-related behaviour and sensory abnormalities (i. LÄS MER

4. 3. Pain among women : Prospective population studies from a biopsychosocial perspective on pain

   Författare :Johanna Thomtén; Örjan Sundin; Joaquim J. F. Soares; Bo Melin; Mittuniversitetet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; psychosocial factors; pain; socio-economic status; quality of life; burnout; women;

   Sammanfattning : This thesis focuses on the role of different psychosocial factors in the course of pain over time in a general population sample of women in Sweden. The main aim was to identify and quantify such factors as predictors of pain, pain-related disability and quality of life within a biopsychosocial framework for the understanding of the pain experience over time. LÄS MER

5. 4. Postoperative Intrathecal Pain Treatment in Children

   Författare :Karin Hesselgard; Neurokirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatri; intensivvård; Pediatrics; Anaesthesiology; intensive care; Anestesiologi; Pain measurement; Intrathecal pain treatment; Children;

   Sammanfattning : Selective dorsal rhizotomy (SDR) is an effective operations method that successfully decreased the degree of spasticity with long lasting beneficial effects for children with spastic diplegia. Children undergoing SDR are postoperatively in severe pain, a pain related to both the extensive surgical exposure with multilevel laminotomy and the nerve root manipulation. LÄS MER

7. 5. Neurotransmission in CNS regions involved in pain modulation : neurochemical effects of analgesic drugs and spinal cord stimulation in the spinal cord and midbrain periaqueductal grey of the rat

   Författare :Carl-Olav Stiller; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Adenosine; dorsal horn; GABA; microdialysis; neurotensin; opioids; periaqueductal gray; sciatic nerve lesion; receptor binding; spinal cord stimulation; substance P.;

   Sammanfattning : The dorsal hom of the spinal cord and the midbrain penaqueductal grey matter (PAG) are important regions for pain modulation. In this thesis the effects of opioids and spinal cord stimulation (SCS) on the release of gamma-amino butyric acid (GABA), substance P (SP) and neurotensin (NT) were investigated in these regions of the rat by in vivo microdialysis. LÄS MER