Sökning: "metabolic inhibition"

Visar resultat 31 - 35 av 209 avhandlingar innehållade orden metabolic inhibition.

  1. 31. 11beta-Hydroxysteroid dehydrogenase type 1 as a pharmacological target in metabolic disease

    Författare :Malin Hult; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The metabolic syndrome is a collection of associated disorders, affected by lifestyle, genetic predisposition and environment, and emerges as a consequence of the Western society lifestyle. It describes a variety of cardiovascular and atherosclerotic risk factors including insulin resistance, obesity, dyslipidemia and arterial hypertension. LÄS MER

  3. 32. The role of growth factors in white fat browning and metabolic disease

    Författare :Carina Fischer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The adipose tissue is composed of a variety of cell types that constantly cross-communicate with each other to allow the tissue to operate and to adapt to various external stimuli. The diversity of these cell populations and their production of secretory factors define not only adipose tissue morphology, but also its function. LÄS MER

  4. 33. Metabolic Engineering of the Pentose Phosphate Pathway of Xylose Fermenting Saccharomyces cerevisiae

    Författare :Björn Johansson; Teknisk mikrobiologi; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Kemiteknik och kemisk teknologi; Chemical technology and engineering; xylulokinase; pentose phosphate pathway; genetic engineering; Saccharomyces cerevisiae; xylose; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : The aim of the work presented in this thesis is the improvement of xylose fermentation performance of recombinant Saccharomyces cerevisiae strains expressing XYL1 and XYL2 from Pichia stipitis, encoding xylose reductase (XR) and xylitol dehydrogenase (XDH). A recombinant strain of S. LÄS MER

  5. 34. Genetic and metabolic studies towards personalized conditioning regimen prior to stem cell transplantation

    Författare :Ibrahim El-Serafi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hematopoietic stem cell transplantation (HSCT) is a curative treatment for several malignant and non- malignant diseases. The busulphan (Bu)/cyclophosphamide (Cy) combination is one of the most common conditioning regimens given prior to HSCT. LÄS MER

  7. 35. Ammonia assimilation and nitrogen fixation in phototrophic bacteria : studies on glutamine synthease and the metabolic regulation of nitrogenase in Rhodospirillum rubrum

    Författare :Abdelhamid Soliman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The phototrophic bacteria and a few other species, are able to control nitrogen fixation on the metabolic level. This is a fast and reversible mechanism, which “switches off and on” the nitrogenase activity in response to the accessibility of combined nitrogen, the energy supply and the level of oxygen in the medium. LÄS MER