Sökning: "metabolic inhibition"
Visar resultat 16 - 20 av 208 avhandlingar innehållade orden metabolic inhibition.
16. Polyamine Pathway as Drug Target against Malaria
Sammanfattning : Malaria, caused by the protozoan parasite Plasmodium falciparum is responsible for about 600.000 death cases every year. Mainly affected are populations of subtropical countries in Africa and the largest groups of victims are children below the age of 5 years. LÄS MER
17. Microbial Production of Bio-Based Chemicals: A Biorefinery Perspective
Sammanfattning : A shift from fossil- to renewable biomass feedstock for the emerging bio-based economy requires the development and adoption of new sustainable technologies that are more suited for transformation of biomass components to chemicals, materials and energy. This thesis presents investigations on the development of processes based on industrial biotechnology as a key element for the production of chemicals from agro-/industrial by-products. LÄS MER
18. Improving initial xylose metabolism in recombinant Saccharomyces cerevisiae
Sammanfattning : The aim of the thesis is to improve the initial steps of xylose metabolism in recombinant Saccharomyces cerevisiae. S. cerevisiae takes up xylose of poor affinity by means of hexose transporters. Metabolic control analysis was used to investigate whether the low xylose utilisation rate is due to inefficient transport. LÄS MER
19. Novel aspects of metabolic regulation and inflammation in human adipocytes
Sammanfattning : The significance of adipose tissue and obesity has been recognized in numerous pathologies. However, the mechanisms behind this connection are not yet completely understood. LÄS MER
20. Differential microRNA and metabolic expressions in neuroendocrine and cervical carcinomas
Sammanfattning : MicroRNAs (miRNAs) are important regulators of many biological processes involved in cancer development and progression. However, the functional roles of miRNAs in some cancer types are still poorly understood. LÄS MER