Sökning: "medical benefit"

Visar resultat 6 - 10 av 672 avhandlingar innehållade orden medical benefit.

  1. 6. New targeted therapies for malignant neural tumors : From systematic discovery to zebrafish models

    Författare :Elin Almstedt; Sven Nelander; Rogier Versteeg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroblastoma; glioblastoma; data integration; zebrafish models; precision medicine; Oncology; Onkologi; Medical Cell Biology; Medicinsk cellbiologi; Medical Informatics; Medicinsk informatik; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Cancers in the neural system presents a major health challenge. The most aggressive brain tumor in adults, glioblastoma, has a median survival of 15 months and few therapeutic options. High-risk neuroblastoma, a childhood tumor originating in the sympathetic nervous system, has a 5-year survival under 50%, despite extensive therapy. LÄS MER

  2. 7. X-ray and neutron μCT of biomedical samples: from image acquisition to quantification

    Författare :Niccoló Peruzzi; Lund Medicinsk strålningsfysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; x-ray imaging; neutron imaging; μCT; synchrotron radiation; x-ray phase-contrast; nanoholotomography; x-ray elemental mapping; biomedical applications; virtual histology; biodegradable implants; Mg-alloys; enteric nervous system; peripheral neuropathy; gastroenteric dysmotility; Fysicumarkivet A:2021:Peruzzi;

    Sammanfattning : Even though the validity of x-ray computed tomography in the analysis of biomedical samples is nowadays undisputed, the more recent imaging techniques and more advanced instruments (such as synchrotrons) are still relatively unknown to many medical doctors that could benefit from them.The doctoral work presented in this thesis joins a collective effort from the imaging community to demonstrate potential applications of advanced x-ray and neutron imaging methods to preclinical medical research, with the hope of contributing to reach a “critical mass” in the medical community and in the public opinion as well. LÄS MER

  3. 8. Practical Implementation of Quality Assurance Guidelines for Hyperthermia Therapy

    Författare :Mattia de Lazzari; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hyperthermia; quality assurance; tissue-mimicking phantoms;

    Sammanfattning : Hyperthermia therapy (HT) has been proven to be a potent enhancer of chemotherapy and radiotherapy in numerous clinical trials. The effectiveness of HT is strictly dependent on the administered thermal dose, which, in turn, is dependent on the quality of the therapeutic heat applied to the patient. LÄS MER

  4. 9. Minimally Invasive Catheter-Based Technologies

    Författare :Mikael Sandell; Göran Stemme; Staffan Holmin; Niclas Roxhed; Wouter van der Wijngaart; Stefan Jonsson; Duncan Maitland; KTH; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicinsk teknologi; Medical Technology;

    Sammanfattning : A simple incision procedure in a blood vessel makes the entire vascular system accessible. Through contrast injection and X-ray visualization, the vascular tree can be mapped and navigated through manual manipulation of thin tubes and wires. LÄS MER

  5. 10. Development of a polymer based neural probe - How to record intracortical neural activity while minimizing the tissue response

    Författare :Fredrik Ejserholm; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Neural Probes; Electrode Modification; Polymer; Neurophysiology; OSTE ;

    Sammanfattning : Intracortical neural probes have in the last couple of years been developed from stiff single probes to stiff multi-electrode neural probes to flexible multi-electrode neural probes. One reason for the change in design is that more than one recording/stimulation electrode, as in the case with a single wire, is needed for more advanced studies. LÄS MER