Sökning: "precision medicine"

Visar resultat 1 - 5 av 201 avhandlingar innehållade orden precision medicine.

  1. 1. New targeted therapies for malignant neural tumors From systematic discovery to zebrafish models

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Elin Almstedt; Sven Nelander; Rogier Versteeg; [2020]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroblastoma; glioblastoma; data integration; zebrafish models; precision medicine; Oncology; Onkologi; Medical Cell Biology; Medicinsk cellbiologi; Medical Informatics; Medicinsk informatik; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Cancers in the neural system presents a major health challenge. The most aggressive brain tumor in adults, glioblastoma, has a median survival of 15 months and few therapeutic options. High-risk neuroblastoma, a childhood tumor originating in the sympathetic nervous system, has a 5-year survival under 50%, despite extensive therapy. LÄS MER

  2. 2. Studies on Heparin Binding protein in bacterial infections

    Detta är en avhandling från Department of Clinical Sciences, Lund University

    Författare :Adam Linder; Lund University.; Lunds universitet.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Infectious diseases remain a major health problem, where sepsis and other severe bacterial infections are common causes of morbidity and mortality, and are associated with high costs for the community. The importance of early and appropriate treatment of sepsis and severe bacterial infections has been underlined by many and since sepsis is more prevalent and has a higher mortality rate than for instance acute myocardial infarction, there is a need for improvement. LÄS MER

  3. 3. The Voice of the Patient

    Detta är en avhandling från Respiratory Medicine and Allergology, Lund University

    Författare :Hampus Kiotseridis; Lund University.; Lunds universitet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rhinitis; asthma; Patient-reported outcome; health-related quality of life; Children; asthma control; pollen warning; grass pollen allergy;

    Sammanfattning : Allergic diseases, which constitute a global health problem, have been defined as one of the epidemics of the twenty-first century. Since there are no cures for allergic diseases today, the goal of treatment is to get the disease under control so that the patient can live a normal life with optimal chances of development. LÄS MER

  4. 4. In Vivo Accuracy and Precision in Prosthodontics

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Robert Nedelcu; Andreas Thor; Ingela Nyström; Pontus Olsson; Per Vult von Steyern; [2020]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; accuracy; precision; in vivo; digital impression; intraoral scanner; polyether impression; implant impression; framework misfit; fully edentulous; Oral and Maxillofacial Surgery; Käkkirurgi; Oral and Maxillofacial Surgery; Käkkirurgi;

    Sammanfattning : Background: There has been a dramatic increase in commercially available intraoral scanners (IOS) in the last decade, offering to replace indirect digitization of models (MOD) fabricated from impressions (IMPR). IOS has benefits of less patient discomfort and a faster workflow to fabricate fixed dental prosthesis (FDP), and implant-supported prostheses (IFD). LÄS MER

  5. 5. Studies on cell wall-attached proteins of Streptococcus pyogenes

    Detta är en avhandling från Tornavagen 10, BMC B14, 221 84 Lund

    Författare :Magnus Rasmussen; Lund University.; Lunds universitet.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insertion sequence; phase variation; collagen-like; alpha2-macroglobulin; pattern; virulence; surface protein; Stretococcus pyogenes; cell wall-attached protein; Clinical biology; Klinisk biologi;

    Sammanfattning : Cell wall-attached proteins (CWPs) are important for the virulence of Gram-positive bacteria, but are also targets for the host immune system. CWPs have a conserved COOH-terminal region, responsible for cell wall-sorting. A pattern based on this conserved region was developed. LÄS MER