Sökning: "kidney response"

Visar resultat 21 - 25 av 153 avhandlingar innehållade orden kidney response.

  1. 21. Molecular mechanisms behind the liver-induced acceptance of renal grafts in highly sensitized patients

    Författare :Madeleine Ingelsten; Göteborgs universitet; []
    Nyckelord :kidney transplantation; liver tolerance; HLA antibodies; dendritic cells; indoleamine 2; 3-dioxygenase; IL-10; natural killer cells;

    Sammanfattning : Preformed antibodies directed at donor HLA are considered an absolute contraindication for kidney transplantation, because of the high risk of rejection. Thus, patients with high levels of HLA antibodies have little chance of receiving a kidney transplant. LÄS MER

  3. 22. Molecular determinants of disease severity in urinary tract infection

    Författare :Ines Ambite; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Asymptomatic bacteriuria; urinary tract infection; acute pyelonephritis; cystitis; Escherichia coli 83972; host response; NlpD; RNA Polymerase II; transcription regulation; inflammasome; Il-1β; ASC; NLRP-3; hyper-inflammatory disorder; MMP-7; IL-1RA; genetic susceptibility; IRF-7; siRNA therapy; P fimbriae; type 1 fimbriae;

    Sammanfattning : In the urinary tract, Escherichia coli infection may result in life-threatening disease, or asymptomatic bacterial carriage, comparable to bacterial commensalism in the gut. Pathogenic strains trigger a disease provoking host response which differs depending on the infected organ. LÄS MER

  4. 23. Identification and characterization of kidney glomerulus-associated genes and proteins

    Författare :Ljubica Perisic; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The kidney glomerulus is a micro-organ comprised of a molecular filtration barrier that prevents the loss of blood proteins into the primary filtrate. This function is dependent on the coordination of its three constituent layers: the endothelium, the glomerular basement membrane and the podocytes. LÄS MER

  5. 24. Biology of lithium response in bipolar disorder : genetic mechanisms and telomeres

    Författare :Lina Martinsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Bipolar;

    Sammanfattning : Background: Bipolar disorder is a common, chronic and severe mental illness, causing suffering and large costs. Lithium treatment is the golden standard and works in 2/3 of patients, of which 50% are called lithium responders. LÄS MER

  7. 25. Foxi1, an important gene for hearing, kidney function and male fertility

    Författare :Hilmar Vidarsson; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : Aim: In this study we focused on the biological importance of the forkhead transcription factor Foxi1. The overall aim was to elucidate the functional role of Foxi1 in the inner ear, kidney and epididymis. LÄS MER