Sökning: "liver tolerance"

Visar resultat 1 - 5 av 61 avhandlingar innehållade orden liver tolerance.

  1. 1. On the regulation of immune responses to dietary and self antigens

    Författare :Susanne Lindgren; Göteborgs universitet; []
    Nyckelord :Tolerance; regulatory T cells; self antigens; oral tolerance; dietary antigens; intestinal epithelial cells; exosomes; Staphylococcus aureus enterotoxin A;

    Sammanfattning : Regulatory mechanisms are necessary to avoid the misdirected aggressive immune responses responsible for the pathology seen in autoimmunity and allergy. Thymic-derived CD4+CD25+ regulatory T cells are indispensible for this regulation. We investigated if CD4+CD25+ Treg prevents auto-reactive responses in adult peripheral blood and cord blood. LÄS MER

  3. 2. Molecular mechanisms behind the liver-induced acceptance of renal grafts in highly sensitized patients

    Författare :Madeleine Ingelsten; Göteborgs universitet; []
    Nyckelord :kidney transplantation; liver tolerance; HLA antibodies; dendritic cells; indoleamine 2; 3-dioxygenase; IL-10; natural killer cells;

    Sammanfattning : Preformed antibodies directed at donor HLA are considered an absolute contraindication for kidney transplantation, because of the high risk of rejection. Thus, patients with high levels of HLA antibodies have little chance of receiving a kidney transplant. LÄS MER

  4. 3. Aspects on the Diverse Manifestations of Cystic Fibrosis

    Författare :Helga Elidottir; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cystic fibrosis; Glucose tolerance; Diabetes; Liver disease; Continuous glucose monitoring; Oral glucose tolerance test; Lung function; Epidemiolgy; N1303K variant;

    Sammanfattning : .... LÄS MER

  5. 4. Immune interactions with the liver

    Författare :Azza Karrar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Liver sinusoid; endothelial cells; apoptosis; antibodies; liver immunity; biliary cells; autoimmune liver diseases; estrogen;

    Sammanfattning : The liver has an important role in the induction of immune tolerance and can be a target for immune mediated damage. The following studies are performed to address the role of liver sinusoidal endothelial cells (LSEC) in tolerance induction and to understand some of the mechanisms involved in the pathogenesis of primary sclerosing cholangitis (PSC). LÄS MER

  7. 5. Mechanisms of liver allograft rejections

    Författare :Xupeng Ge; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Liver transplantation; acute rejection; antibody; biliary epithelial cell; sinusoidal endothelial cell; cholangitis; toll-like receptor;

    Sammanfattning : Liver transplantation (M) has become a standard treatment for many end-stage liver diseases. However, acute rejections still occur in about half of the liver transplant recipients even treated with a combination of different modem immunosuppressants. LÄS MER