Sökning: "kidney response"

Visar resultat 26 - 30 av 153 avhandlingar innehållade orden kidney response.

  1. 26. Chronic kidney disease : a complex network of leukocyte dysfunction and inflammation

    Författare :Ladan Mansouri; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic kidney disease (CKD) is a common medical condition with a prevalence of up to 13% worldwide. The insidious loss of renal function develops over time to reach end stage renal disease (ESRD) when the kidneys are unable to remove toxins and interventions such as dialysis or kidney transplantation are mandatory. LÄS MER

  2. 27. Assessment and monitoring of nutritional status in chronic kidney disease patients

    Författare :Thiane Gama-Axelsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Patients with chronic kidney disease (CKD) often suffer from malnutrition and protein-energy wasting (PEW) resulting in poor nutritional status which is a powerful predictor of mortality. As it is not clear how well nutritional markers used in the clinical care of these patients accurately reflect nutritional status we evaluated in post-hoc, cross-sectional observational studies several common markers of malnutrition and PEW, and assessed their correlations to each other and to survival in patients with CKD stage 5 (CKD 5). LÄS MER

  3. 28. The role of FGF23/Klotho in mineral metabolism and chronic kidney disease

    Författare :Hannes Olauson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic kidney disease (CKD) is a global health burden of growing incidence and prevalence. As renal function declines disturbances in mineral metabolism, such as hyperphosphatemia and secondary hyperparathyroidism, inevitably develop. These metabolic changes are closely associated with poor prognosis and survival. LÄS MER

  4. 29. The dynamics of intra- and inter-organ communication during an acute kidney infection

    Författare :Svava Steiner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis focuses on the roles of neuro-immune communication and infection-mediated coagulation during bacterial kidney infections. We demonstrate dynamic intra- and inter-organ host responses, where the outcome of an infection depends on both bacterial and host factors. LÄS MER

  5. 30. The developing rat kidney : the dopamine system and related serine/threonine kinases and phosphatases

    Författare :Johan Svennilson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :apoptosis; confocal immunofluorescence; DARPP-32; dopamine; foetal renal development; hypertension; in situ hybridization; metanephric culture; mouse; nephron number; PKC; PP1 PP2A; protein phosphorylation; rat;

    Sammanfattning : The kidney originates from the fusion and conversion of two tissues: the metanephric mesenchyme and the ureter epithelium, an evagination from the Wolffian duct. Although a number of candidate molecules have been shown to be of importance for the differentiation of the embryonic kidney, many of the signalling pathway leading to this development are still obscure. LÄS MER