Sökning: "isothiocyanates"

Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet isothiocyanates.

  1. 1. The fruit fly Drosophila melanogaster GSTE6 and E7; characterization, immobilization and transgenic overexpression

    Författare :Muhammad Aslam; Bengt Mannervik; Ralf Morgenstern; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glutathione transferases; drosophila melanogaster; isothiocyanates; toxicity; immobilization; kinetics; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Glutathione transferases (GSTs) are multifunctional enzymes that are universally distributed in most eukaryotes and prokaryotes. They play a pivotal role in the metabolism and detoxication of numerous endogenous and exogenous electrophiles by conjugating them with ubiquitous tripeptide glutathione. LÄS MER

  3. 2. Studies on Human and Drosophila melanogaster Glutathione Transferases of Biomedical and Biotechnological Interest

    Författare :Aslam M.A. Mazari; Bengt Mannervik; Philip Board; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; glutathione transferases; detoxication; hpgds inhibition; immobilization; isothiocyanates; drosophila GSTs; environmental pollutants; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Glutathione transferases (GSTs, EC.2.5.1. LÄS MER

  4. 3. The Quest for Functional Quasi-Species in Glutathione Transferase Libraries

    Författare :Arna Rúnarsdóttir; Bengt Mannervik; Ralf Morgenstern; Uppsala universitet; []
    Nyckelord :glutathione transferase; directed evolution; multivariate analysis; quasi-species; isothiocyanates; Biokemi; Biochemistry;

    Sammanfattning : Glutathione transferases (GSTs) are good candidates for investigations of enzyme evolution, due to their broad substrate specificities and structural homology. The primary role of GSTs is to act as phase II detoxifying enzymes protecting the cell from toxic compounds of both endo- and exogenous origins. LÄS MER

  5. 4. Analytical methodologies for common skin allergens : Organic thioureas, isothiocyanates and fragrance hydroperoxides in everyday life products

    Författare :Ahmed Gamal Ramzi; Ulrika Nilsson; Anneli Julander; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemical analysis; contact allergy; chloroprene rubber; diethyl thiourea; ethyl isothiocyanate; fragrance hydroperoxides; Analytical Chemistry; analytisk kemi;

    Sammanfattning : This thesis describes analytical methodologies for the determination of important skin-sensitizing chemicals in two types of commercial items: chloroprene rubber and fragrance products which are both well-known to be associated with contact allergy.Chloroprene rubber (neoprene) is widely used in different applications and products, such as bags, gloves, wetsuits, braces, mouse pads et c. LÄS MER

  7. 5. Isothiocynates as skin sensitizers. Bioactivation and distribution in skin and draining lymph nodes

    Författare :Kristin Samuelsson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Development of contact dermatitis can be caused by electrophilic compounds (haptens) or prohaptens that come into contact with the skin. A prohapten is a compound seemingly harmless at first sight that can be transformed into reactive metabolites by metabolizing enzymes in the skin to become a hapten. LÄS MER