Sökning: "Glutathione transferases"

Visar resultat 1 - 5 av 59 avhandlingar innehållade orden Glutathione transferases.

  1. 1. Glutathione transferases : molecular cloning, site-directed mutagenesis and structure-function studies

    Författare :Gun Stenberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Three distinct glutathione transferases (GST) cDNA clones were obtained by screening of tumour cell line cDNA libraries. The cDNA clones were expressed in Escherichia coli and the enzymes characterized. Rat GST 8-8 is the only member in the multifunctional GST family for which a specific cellular function has been proposed. LÄS MER

  3. 2. Glutathione transferases : studies on the structure and function of recombinant enzymes

    Författare :Mikael Widersten; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  4. 3. Cytosolic glutathione transferases : inhibition characteristics as new criteria for identification of different isoenzymes and demonstration of class Pi enzymes in normal mammalian tissues and tumor cells

    Författare :Muhammad Kalim Tahir; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  5. 4. Cytosolic glutathione transferases : classification and aspects of structure and function

    Författare :Per Ålin; Stockholms universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  7. 5. Role of Multiple Glutathione Transferases in Bioactivation of Thiopurine Prodrugs : Studies of Human Soluble Glutathione Transferases from Alpha, Kappa, Mu, Omega, Pi, Theta, and Zeta Classes

    Författare :Birgitta I. Eklund; Bengt Mannervik; Mikael Widersten; Ralf Morgenstern; Uppsala universitet; []
    Nyckelord :Biochemistry; Glutathione Transferases; Thiopurines; Prodrug; Bioactivation; Screening Method; Chemotherapy; Functional plasticity; Modulated activity; Biokemi;

    Sammanfattning : A screening method was developed for identification of catalytically active enzymes in combinatorial cDNA libraries of mutated glutathione transferase (GST) derivatives expressed in E. coli. The method is based on spraying monochlorobimane (MCB) directly over bacterial colonies growing on agar. LÄS MER