Sökning: "toxicity"

Visar resultat 1 - 5 av 875 avhandlingar innehållade ordet toxicity.

  1. 1. Towards new computational tools for predicting toxicity

    Författare :Swapnil Chavan; Ian Nicholls; Scott Boyer; Linnéuniversitetet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Acute toxicity; chronic toxicity; hERG; k-NN; LD50; LOEL; Munro database; QSAR; read-across; toxicity; Medicinsk kemi; Medical Chemistry;

    Sammanfattning : The toxicological screening of the numerous chemicals that we are exposed to requires significant cost and the use of animals. Accordingly, more efficient methods for the evaluation of toxicity are required to reduce cost and the number of animals used. LÄS MER

  2. 2. Environmental and health hazards of chemicals in plastic polymers and products

    Författare :Delilah Lithner; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :plastics; plastic products; plastic polymers; consumer products; environmental hazards; environment; health hazards; human health; hazard ranking; hazard assessment; chemical ranking; hazard identification; hazard classifications; hazardous chemicals; hazardous substances; toxic substances; monomers; polymers; toxicity; acute toxicity; toxicity tests; Daphnia magna; Toxicity Identification Evaluation; TIE; leaching; leachates; product leachates; leaching tests; plastic materials; plastic;

    Sammanfattning : Plastics are extremely diverse in terms of chemical composition, properties and possible applications, and are widely distributed in the society and the environment. In the last 15 years the global annual production has doubled, reaching 245 million tons in 2008. LÄS MER

  3. 3. Comparative avian developmental toxicity of PFAAs

    Författare :Marcus Nordén; Magnus Engwall; Krister Halldin; Anders Bignert; Örebro universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; chicken; herring gull; cormorant; PFAA; PFOS; PFOA; toxicity; levels; Biology; Biologi;

    Sammanfattning : Perfluoroalkyl acids (PFAAs) are persistent organic pollutants that can commonly be found in environmental matrixes and wildlife from all over the globe. The PFAAs have been used in applications such as water and dirt repelling treatments for textiles, oil-resistant paper coatings and fire-fighting foams. LÄS MER

  4. 4. Analysis of Perfluoroalkyl Acids in Swedish Biota : Temporal trends, tissue distribution and toxicity

    Författare :Katrin Holmström; Urs Berger; Gregg Tomy; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Environmental chemistry; PFOS; PFAS; pollutant; Baltic guillemot; peregrine falcon; Monoporeia affinis; time trend; toxicity; Environmental chemistry; Miljökemi; Persistent organic compounds; Persistenta organiska föreningar; Applied Environmental Science; tillämpad miljövetenskap;

    Sammanfattning : Perfluorinated alkyl acids (PFAS) are ubiquitous environmental contaminants. They are found in high concentrations in top predators worldwide, with perfluorooctane sulfonate (PFOS) as the predominant compound. LÄS MER

  5. 5. Modelling late toxicity in hypofractionated radiation therapy

    Författare :Niclas Pettersson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; Göteborgs universitet; Gothenburg University; []
    Nyckelord :Hypofractionation; normal tissue complication probability; modelling; linear-quadratic model; fractionation sensitivity; late toxicity; radiation-induced rib fracture; genitourinary toxicity; stereotactic body radiation therapy; high-dose-rate brachytherapy; multimodality radiation therapy; patient-reported outcomes; prostate cancer; nsclc;

    Sammanfattning : In hypofractionated radiation therapy (RT), the treatment is delivered by few fractions with high doses per fraction. This is in contrast to conventionally fractionated RT where the total dose is delivered in many fractions with low doses per fraction. LÄS MER