Sökning: "insulin autoantibodies"

Visar resultat 36 - 40 av 49 avhandlingar innehållade orden insulin autoantibodies.

1. 36. Studies of Enterovirus Infection and Induction of Innate Immunity in Human Pancreatic Cells

   Författare :Mahesh Anagandula; Magnus Essand; Didier Hober; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 Diabetes; Enterovirus; Innate Immunity; Pancreas;

   Sammanfattning : Several epidemiological and clinical studies have indicated a possible role of Enterovirus (EV) infection in type 1 diabetes (T1D) development. However, the exact casual mechanism of these viruses in T1D development is not known. LÄS MER

3. 37. Diabetes in Young Adults : Remission, β-cell function and markers of inflammation

   Författare :Anna Schölin; Elisabeth Björk; Anders Karlsson; Jan Åman; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Internal medicine; type 1 diabetes; young adults; remission; β-cell function; islet antibodies; gender; CRP; Invärtesmedicin; Internal medicine; Invärtesmedicin; Internal Medicine; invärtesmedicin;

   Sammanfattning : Type 1 diabetes is caused by immuno-mediated β-cell destruction leading to insulin deficiency and hyperglycaemia. The decline in β-cell function and the clinical course after diagnosis vary. Whether the process of destruction of the β-cells is associated with markers of a non-specific inflammatory response is unknown. LÄS MER

4. 38. Metab-Immune analysis of the non-obese diabetic mouse

   Författare :Viqar Banday; Kristina Lejon; Åsa Andersson; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NOD mouse; Type 1 diabetes; B cells; glutamic acid; metabolomics; immunologi; Immunology;

   Sammanfattning : Type 1A diabetes mellitus or T1D is a chronic disease characterized by T cell mediated destruction of the insulin producing β cells in the islets of Langerhans. The classical symptoms include high glucose levels in urine and blood, polyuria, and polydipsia. LÄS MER

5. 39. Anomalies in humoral immunity in the NOD mouse : contribution to the progression of type 1 diabetes

   Författare :Radha Thyagarajan; Kristina Lejon; Per-Arne Oldenborg; Susanna Cardell; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 Diabetes; NOD mouse; B cells; IgE; TACI; BAFF; immunologi; Immunology;

   Sammanfattning : The non-obese diabetic (NOD) mouse is widely used model Type 1 diabetes (T1D), a chronic inflammatory disease characterized by destruction of the insulin producing β cells in the islets of Langerhans by immune cells. The classical symptoms include increased glucose levels in urine and blood, frequent urination and enhanced thirst. LÄS MER

7. 40. Genetic and serological characteristics of tissue-specific autoimmune disease

   Författare :Daniel Eriksson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The immune system has evolved to protect us from infectious disease and not to overreact to our own tissues or commensal flora. Immune system attack directed against self-tissue is referred to as autoimmune disease, a group of diseases that affect more than 5% of the population. LÄS MER