Sökning: "BAFF"

Visar resultat 1 - 5 av 24 avhandlingar innehållade ordet BAFF.

  1. 1. Anomalies in humoral immunity in the NOD mouse : contribution to the progression of type 1 diabetes

    Författare :Radha Thyagarajan; Kristina Lejon; Per-Arne Oldenborg; Susanna Cardell; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 Diabetes; NOD mouse; B cells; IgE; TACI; BAFF; immunologi; Immunology;

    Sammanfattning : The non-obese diabetic (NOD) mouse is widely used model Type 1 diabetes (T1D), a chronic inflammatory disease characterized by destruction of the insulin producing β cells in the islets of Langerhans by immune cells. The classical symptoms include increased glucose levels in urine and blood, frequent urination and enhanced thirst. LÄS MER

  3. 2. A radical view of haemoglobin - protein engineering and characterisation

    Författare :Marie Grey; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; His-Gln tagging; protein purification; blood substitutes; radical scavenging; superoxide dismutase; E. coli; diglobin; Haemoglobin; protein engineering; aqueous two-phase systems; hydrophobic interaction chromatography;

    Sammanfattning : In recent years shortages of donated blood have become a growing problem for health care systems world-wide. Blood substitutes based on human haemoglobin (Hb) could potentially ameliorate this situation. However, clinical trials have indicated problems due to e.g. LÄS MER

  4. 3. Stochastic Event-Based Control and Estimation

    Författare :Toivo Henningsson; Institutionen för reglerteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; event-based control; event-based estimation; sporadic control; stochastic control; stochastic hybrid systems; sum-of-squares methods; control over networks; quantized measurements;

    Sammanfattning : Digital controllers are traditionally implemented using periodic sampling, computation, and actuation events. As more control systems are implemented to share limited network and CPU bandwidth with other tasks, it is becoming increasingly attractive to use some form of event-based control instead, where precious events are used only when needed. LÄS MER

  5. 4. The role of autoantibodies in inflammatory myopathies

    Författare :Sevim Barbasso Helmers; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Idiopathic inflammatory myopathies; polymyositis; dermatomyositis; inclusion body myositis; ILD; IVIG; IFN; BAFF; endothelial cells; anti-Jo-1;

    Sammanfattning : Polymyositis (PM), dermatomyositis (DM) and inclusion body myositis (IBM), collectively called myositis, are chronic inflammatory myopathies. These disease subsets are heterogeneous but share some features, such as skeletal muscle weakness and inflammatory cell infiltrates in muscle tissue. LÄS MER

  7. 5. B-cell survival factors in multiple sclerosis and myasthenia gravis

    Författare :Mathula Thangarajh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) is a chronic, progressive neurological disease in which death of myelin-producing oligodendrocytes and axonal damage are prominent pathological features. The cause of MS is unknown but genetic and environmental factors have been proposed to be important. LÄS MER