Sökning: "innate immune activation"

Visar resultat 16 - 20 av 279 avhandlingar innehållade orden innate immune activation.

  1. 16. Innate regulation of the adaptive immune system during autoimmunity

    Författare :Roham Parsa; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Immune activation comprises multiple biological checkpoints to ensure proper and regulated effector functions. Phagocytes such as macrophages, dendritic cells and neutrophils have important functions during inflammation, e.g. clearance of bacterial pathogens. LÄS MER

  3. 17. The Role of Innate Immunity in Islet Transplantation : Clinical and Experimental Studies

    Författare :Lisa Moberg; Bo Nilsson; Olle Korsgren; Kristina Nilsson Ekdahl; Rolf Larsson; David Harlan; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; diabetes; islet transplantation; islet of Langerhans; coagulation activation; IBMIR; tissue factor; thrombin; inactivated FVIIa; melagatran; neutrophilic granulocyte; Immunologi; Immunology; Immunologi;

    Sammanfattning : Clinical islet transplantation is an emerging procedure to cure type 1 diabetes. The graft is implanted by infusion into the liver through the portal vein. A major obstacle that still needs to be overcome is the requirement for islets from multiple donors to achieve insulin independence. LÄS MER

  4. 18. Innate mechanisms regulating B cell activation in inflammatory diseases

    Författare :Sara Lind; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Generation of powerful and highly specific immune responses against invading pathogens is essential to our survival. However, the immune system can cause disease if activated in an inappropriate manner. LÄS MER

  5. 19. NK cell and dendritic cell interactions in innate immune responses

    Författare :Catrine M Persson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NK cells; Dendritic cells; crosstalk; recruitment; activation; CD94 NKG2AQa1; Toxoplasma gondii;

    Sammanfattning : Natural killer (NK) cells are cytotoxic cells of the innate immune system. They have been found to be critical in the defense against infections and also against some tumors. Recent studies have shown that NK cells require signals from accessory cells to induce their recruitment and activation at the site of infection or tumor growth. LÄS MER

  7. 20. Stress and immune signaling in a Drosophila tumor model

    Författare :Dilan Khalili; Ulrich Theopold; Mirka Uhlirova; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drosophila; cancer; innate immunity; fibrosis; antimicrobial peptides; chitinase-like proteins; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Cancer cells contain multiple biological alterations that allow them to escape from host surveillance mechanisms. One of the mechanisms that play an essential role in host protection against tumor growth is immunity. LÄS MER