Sökning: "Toxoplasma gondii"

Visar resultat 1 - 5 av 23 avhandlingar innehållade orden Toxoplasma gondii.

  1. 1. Transmigration of Toxoplasma gondii across biological barriers

    Författare :Emily C. Ross; Antonio Barragan; Ildiko Rita Dunay; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Apicomplexa; blood-brain barrier; leukocyte; immune cell; transendothelial migration; cell adhesion molecule; host-pathogen; FAK; integrin; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Toxoplasma gondii is an obligate intracellular parasite that can likely infect all warm-blooded vertebrates, with estimates of up to 30% of the global human population being infected. Although infection with T. gondii is usually asymptomatic or mild, in immunocompromised individuals infection can lead to lethal toxoplasmic encephalitis. LÄS MER

  3. 2. Host molecular determinants of toxoplasma gondii dissemination

    Författare :Jonas Fuks; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Humans and animals acquire the parasite Toxoplasma gondii through contaminated food or water, upon which the parasite rapidly disseminates in the host. In immunocompetent individuals, this acute phase is transient and leads to chronic colonization of preferentially the central nervous system (CNS). LÄS MER

  4. 3. Immune evasion and dissemination of Toxoplasma gondii

    Författare :Henrik Lambert; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Toxoplasma gondii is an obligate intracellular protozoan parasite which propagates in a complex life cycle where infection of Felidae family-members (Cats) results in sexual recombination whereas all other warm-blooded animals are intermediate hosts. Approximately one third of the human population is estimated to be chronically infected by this parasite. LÄS MER

  5. 4. Molecular diagnosis of infection with Toxoplasma gondii in immunocompromised patients

    Författare :Benjamin Edvinsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Toxoplasma gondii; toxoplasmosis; transplantation; human immunodeficiency virus; polymerase chain reaction; internal amplification control; oligochromatography; Pyrosequencing;

    Sammanfattning : The protozoan parasite Toxoplasma gondii infects more than a billion people worldwide. The parasite is generally divided into three clonal lineages, denoted type I, II and III. LÄS MER

  7. 5. Host-parasite interactions in the dissemination of Toxoplasma gondii

    Författare :Sachie Kanatani; Antonio Barragan; Per Uhlén; Isabelle Tardieux; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Apicomplexa; dendritic cells; microglia; cell migration; 14-3-3 proteins; GABAergic signaling; voltage-dependent calcium channel; host-parasite interaction; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Toxoplasma gondii is an obligate intracellular parasite that infects virtually all warm-blooded organisms. Systemic dissemination of T. gondii in the organism can cause life-threatening infection that manifests as Toxoplasma encephalitis in immune-compromised patients. LÄS MER