Sökning: "immobilized heparin"
Visar resultat 1 - 5 av 7 avhandlingar innehållade orden immobilized heparin.
1. Monocytes, Tissue Factor and Heparin-coated Surfaces : Clinical and Experimental Studies
Sammanfattning : Cardiopulmonary bypass (CPB) is associated with inflammatory response and activation of coagulation. Heparin coating of the CPB circuit is shown to improve the biocompatibility of the surface. The biological effects of a new heparin surface, the Corline Heparin Surface (CHS), prepared according to a new principle, have been studied. LÄS MER
2. Microfluidics in Surface Modified PDMS : Towards Miniaturized Diagnostic Tools
Sammanfattning : There is a strong trend in fabricating miniaturized total analytical systems, µTAS, for various biochemical and cell biology applications. These miniaturized systems could e.g. gain better separation performances, be faster, consume less expensive reagents and be used for studies that are difficult to access in the macro world. LÄS MER
3. Inhibition of the plasma contact system on endpoint immobilized heparin and human endothelium
Sammanfattning : When blood is exposed to foreign materials or injured tissue, several defense systems are activated. The contact with an artificial surface leads to activation of FXII, the first proenzyme of the plasma contact activation system, with concomitant triggering of the intrinsic coagulation and also the fibrinolytic-, kallikrein- and complement systems. LÄS MER
4. Biomaterials and Hemocompatibility
Sammanfattning : Biomaterials are commonly used in the medical clinic today; however, artificial materials can activate the cascade systems in the blood (complement-, coagulation-, contact- and fibrinolytic systems) as well as the platelets to various degrees. When an artificial surface comes in contact with blood, plasma proteins will be adsorbed to the surface within seconds. LÄS MER
5. Thromboinflammation : in a Model of Hepatocyte Transplantation
Sammanfattning : Hepatocyte transplantation is an attractive method for the treatment of metabolic liver disease and acute liver failure. The clinical application of this method has been hampered by a large initial loss of transplanted cells. LÄS MER