Sökning: "hypertoni och diabetes"

Visar resultat 1 - 5 av 24 avhandlingar innehållade orden hypertoni och diabetes.

1. 1. Genetic Factors Contributing to Hypertension. With Emphasis on Hypertension in Type 2 Diabetes

   Författare :Kristina Bengtsson Boström; diabetes och endokrinologi Genomik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endokrinologi; sekretion; diabetologi; Endocrinology; secreting systems; diabetology; primary care; genetics; Hypertension; type 2 diabetes;

   Sammanfattning : The causes of hypertension (HT) and type 2 diabetes (T2DM) are mainly unknown, but they arise from interplay between several genetic and environmental factors. The aim of this thesis was to investigate whether polymorphisms in putative candidate genes for HT increase the susceptibility to HT and/or T2DM. LÄS MER

3. 2. Human glycogen synthase genes. Role in insulin resistance and hypoglycaemia

   Författare :Marju Orho-Melander; diabetes och endokrinologi Genomik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mutation; GYS2; GYS1; glycogen synthase; glycogen; insulin resistance; hypoglycaemia; liver glycogen synthase deficiency; glycogen storage disease type 0; Type 2 diabetes; metabolic syndrome; expression; chromosome 19; 19q13.3; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

   Sammanfattning : Effective insulin-stimulated storage of excess glucose after a meal, and its rapid mobilisation in the fasting state provide basis of glucose homeostasis. Glycogen is the macromolecular storage form of glucose and glycogen synthase (GS) is the rate-limiting enzyme in glycogen synthesis. Skeletal muscle and liver are the major depots of glycogen. LÄS MER

4. 3. Novel Biomarkes in Acute Respiratory Failure and Chronic Obstructive Pulmonary Disease

   Författare :Brynja Jónsdóttir; Kardiovaskulär forskning - hypertoni; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic obstructive pulmonary disease; Dyspnea; Respiratory failure; Biomarkers; GDF-15; ST2; IL-8; noninvasive ventilation; Acute Respiratory Failure; Chronic obstructive pulmonary disease; Dyspnea; Biomarkers; ST2; IL-8; GDF-15; Prognosis and survival; Hypercapnia;

   Sammanfattning : Abstract Background: Dyspnea is a common manifestation of a range of conditions and diseases, sometimes with multiple contributing factors. A subgroup of these patients present with acute hypecapnic respiratory failure (AHRF) and are treated with non-invasive positive pressure ventilation (NPPV). LÄS MER

5. 4. Role of Proneurotensin in Cardiometabolic Diseases

   Författare :Ayesha Fawad; Kardiovaskulär forskning - hypertoni; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine and Health Sciences; Cardiometabolic disease; Obesity : complications; Diabetes; type 2; Proneurotensin; Dyslipidemia;

   Sammanfattning : The burden of cardiometabolic diseases is increasing worldwide. Early detection of high-risk individuals is essential for appropriate diagnosis, better treatment outcomes, quality of life and lower health related costs. LÄS MER

7. 5. Metabolite Alterations and Cardiometabolic Disease: A Nutritional Perspective

   Författare :Einar Smith; Kardiovaskulär forskning - hypertoni; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Metabolomics; Nutrition; Nutritional metabolomics; Biomarkers; Cardiometabolic disease; Cardiovascular disease; Type 2 diabetes; Prospective cohort studies; Dietary intervention;

   Sammanfattning : Background Cardiovascular disease (CVD), type 2 diabetes (T2DM), and atrial fibrillation (AF) collectively impact millions globally, necessitating a comprehensive understanding of preceding metabolic alterations for early intervention. This thesis aims to explore metabolic shifts across populations-based cohorts and evaluate the metabolic impact of a dietary intervention. LÄS MER