Sökning: "19q13.3"
Hittade 3 avhandlingar innehållade ordet 19q13.3.
1. Human glycogen synthase genes. Role in insulin resistance and hypoglycaemia
Sammanfattning : Effective insulin-stimulated storage of excess glucose after a meal, and its rapid mobilisation in the fasting state provide basis of glucose homeostasis. Glycogen is the macromolecular storage form of glucose and glycogen synthase (GS) is the rate-limiting enzyme in glycogen synthesis. Skeletal muscle and liver are the major depots of glycogen. LÄS MER
2. Gene expression profiles at the myotonic dystrophy 1 locus : possible role in disease mechanisms
Sammanfattning : Myotonic dystrophy 1 (DM1) is the commonest adult onset muscular dystrophy, (prevalence 1/8000). The disorder is characterized by anticipation (earlier onset in successive generations, which is accompanied in this disorder by an increase in severity of symptoms) and variable multisystemic symptom presentation. LÄS MER
3. Hypoxia inducible factor 1alpha : molecular mechanisms of regulation
Sammanfattning : Hypoxia-Inducible Factor 1alpha (HIF-1alpha) is an important protein in the homeostatic control of genes in response to low oxygen, or hypoxia. It is thus also a key factor in the regulation of angiogenesis in response to hypoxia, including induction of vascular endothelial growth factor (VEGF) gene expression. LÄS MER