Sökning: "cytochrome c maturation"

Hittade 4 avhandlingar innehållade orden cytochrome c maturation.

  1. 1. Studies on Haemproteins of Gram-positive Bacteria - Implications as Antibacterial Drug Targets

    Författare :Peter Kjelgaard; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bacteriology; virology; mycology; Mikrobiologi; Microbiology; heme; Truncated hemoglobins; cytochrome c maturation; cytochrome bd; ResB; bakteriologi; virologi; mykologi;

    Sammanfattning : With the discovery of antibiotics, several diseases that were previously lethal is today readily cured, or so we thought. Some degree of resistance to one or several antibiotics can be found among many strains of clinical important bacteria. LÄS MER

  3. 2. Apoptosis in myelodysplastic syndromes : effects of hemopoietic growth factors

    Författare :Ramin Tehranchi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Increased apoptosis of hernatopoietic progenitors is a hallmark of myelodysplastic syndromes (MDS) and results in ineffective hematopoiesis. Erythroid apoptosis is thought to be the main mechanism underlying the severe anemia observed in the low-risk subgroups, refractory anemia (RA) arid RA with ringed sideroblasts (RARS). LÄS MER

  4. 3. Molecular characterization of the cancer susceptibility protein wrap53β in Cajal body formation and DNA repair

    Författare :Sofia Henriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : WRAP53β is a multifaceted protein involved in several biological processes including Cajal body maintenance, cancer cell survival and DNA damage repair. By directing factors to Cajal bodies and DNA double-strand breaks (DSBs), WRAP53β facilitates site-specific interactions necessary for proper biological responses. LÄS MER

  5. 4. Kostmann syndrome : a clinical and pathophysiological study

    Författare :Göran Carlsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Kostmann syndrome; severe congenital neutropenia; autosomal recessive; periodontitis; antibacterial peptides; LL-3 7; apoptosis; Bcl-2; granulocyte colony-stimulating factor; glycosylation; lenograstim; filgrastim.;

    Sammanfattning : Kostmann syndrome or severe congenital neutropenia (SCN) is a rare disease, usually diagnosed during the first months of life, characterized by extremely low levels of neutrophils in the peripheral blood, a maturational arrest of the myelopoiesis in the bone marrow and severe bacterial infections. The purpose of this project was to improve the understanding of the clinical course and the pathophysiology of autosomal recessive SCN. LÄS MER