Sökning: "half-time"

Visar resultat 11 - 15 av 22 avhandlingar innehållade ordet half-time.

  1. 11. Proteins of the Inter-α-inhibitor Family : Biosynthesis, Plasma Clearance and Interaction with Extracellular Matrix Components

    Författare :Aneta Kaczmarczyk; Erik Fries; Anders Malmström; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; bikunin; inter-α-inhibitor; pre-α-inhibitor; intracellular processing; plasma clearance; extracellular matrix; binding; collagen; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Sammanfattning : Bikunin, a chondroitin sulfate-containing protein of 25 kDa, has protease inhibitory activity and occurs in the plasma in free and complexed form. In inter-α-inhibitor (IαI) and pre-a-inhibitor (PαI) it is covalently linked through its chondroitin sulfate (CS) chain to two or one other polypeptide of about 80 kDa – heavy chains 1 and 2 (H1, H2) and heavy chain 3 (H3) – respectively. LÄS MER

  3. 12. Studies on oral clearance of citric acid and its effect on enamel erosion

    Författare :Enas Badawi Bashir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Citric acid; Saliva; Site specificity; Degree of saturation; In vitro model; Flow rate; Enamel erosion; Clearance rate; Frequency; Microradiography; Scanning microscopy;

    Sammanfattning : Citric acid in foods is one of the most important factors causing erosionof enamel. The aims were to study citric acid clearance from the oral cavity, the effect of the clearance on the salivary saturation with respect to hydroxyapatite (OHAp) and the effect of the clearance rate and frequency of the citric acid challenges on enamel erosion. LÄS MER

  4. 13. Amyloid beta aggregation kinetics : The role of intrinsic and extrinsic factors

    Författare :Xiaoting Yang; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Alzheimer s disease; Abeta; aggregation; kinetics; secondary nucleation;

    Sammanfattning : Cerebral senile plaque is one of the main pathologies of Alzheimer's disease (AD). The amyloid cascade hypothesis suggests that the aggregation of amyloid beta (Abeta) peptide is involved in the pathogenesis of AD, which is supported by the fact that Abeta overexpression or production of more aggregation-prone variants lead to early-onset dementia. LÄS MER

  5. 14. On gender dysphoria

    Författare :Cecilia Dhejne; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Gender identity refers to an innate and deeply felt psychological identification as a female, male, or some other non-binary gender. Gender identity may be congruent or incongruent with the sex assigned at birth. Gender dysphoria refers to the discomfort or distress that gender incongruence may cause. LÄS MER

  7. 15. Magnetic nanostructured materials for advanced bio-applications

    Författare :Andrea Fornara; Mamoun Muhammed; Josep Nogués; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Materials chemistry; Materialkemi;

    Sammanfattning : In the recent years, nanostructured magnetic materials and their use in biomedical and biotechnological applications have received a lot of attention. In this thesis, we developed tailored magnetic nanoparticles for advanced bio-applications, such as direct detection of antibodies in biological samples and stimuli responsive drug delivery system. LÄS MER