Sökning: "inter-α-inhibitor"

Hittade 2 avhandlingar innehållade ordet inter-α-inhibitor.

  1. 1. Proteins of the Inter-α-inhibitor Family : Biosynthesis, Plasma Clearance and Interaction with Extracellular Matrix Components

    Författare :Aneta Kaczmarczyk; Erik Fries; Anders Malmström; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; bikunin; inter-α-inhibitor; pre-α-inhibitor; intracellular processing; plasma clearance; extracellular matrix; binding; collagen; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Sammanfattning : Bikunin, a chondroitin sulfate-containing protein of 25 kDa, has protease inhibitory activity and occurs in the plasma in free and complexed form. In inter-α-inhibitor (IαI) and pre-a-inhibitor (PαI) it is covalently linked through its chondroitin sulfate (CS) chain to two or one other polypeptide of about 80 kDa – heavy chains 1 and 2 (H1, H2) and heavy chain 3 (H3) – respectively. LÄS MER

  3. 2. Novel Culture Strategies and Signal Transduction Pathways of Pluripotent Stem Cells

    Författare :Sara Pijuan Galitó; Cecilia Annerén; Lena Kjellén; Christopher Ward; Uppsala universitet; []
    Nyckelord :Pluripotent stem cells; Inter-alpha inhibitor; culture method; Biologi med inriktning mot molekylär cellbiologi; Biology with specialization in Molecular Cell Biology; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : Pluripotent stem cells (PSCs) can self-renew indefinitely in culture while maintaining their capacity to differentiate into any cell type of an organism, thus offering novel sources for drug screening, in vitro disease modelling, and cell replacement therapies. However, due to their sensitive nature, many PSC lines are still cultured using undefined components such as serum or serum-derived components, on either feeder cells or complex protein mixes such as Matrigel or gelatine. LÄS MER