Sökning: "glycoprotein G"

Visar resultat 21 - 25 av 56 avhandlingar innehållade orden glycoprotein G.

1. 21. Functional studies of calcein acetoxymethyl ester in human tumor cells

   Författare :Gunnar Liminga; Uppsala universitet; []
   Nyckelord :Medical sciences; Calcein AM; Calcein; Functional assay; Drug resistance; Cytotoxicity; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; klinisk farmakologi; Clinical Pharmacology;

   Sammanfattning : A fluorometric assay for functional measurement of P-glycoprotein 170 (Pgp) mediated transport in cell lines, using the acetoxymethyl ester of calcein (calcein/AM) as a probe was established. The myeloma cell line RPMI 8226/S and the two Pgp-expressing doxorubicin resistant subcell lines 8226/dox6 (low) and 8226/dox40 (high) were used. LÄS MER

3. 22. Pharmacogenetic Studies of Paclitaxel in Ovarian Cancer : focus on interindividual differences in pharmacodynamics and pharmacokinetics

   Författare :Henrik Green; Curt Peterson; Peter Söderkvist; Per Rosenberg; Håkan Melhus; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacogenetics; paclitaxel; LC MS; Taxol; ovarian cancer; pharmacokinetics; CYP2C8; CYP3A4; ABCB1; äggstockscancer; paklitaxel; Clinical pharmacology; Klinisk farmakologi;

   Sammanfattning : Ovarian cancer is one of the most common female cancer diseases in the world today and in Sweden more than 800 new cases are diagnosed every year. The standard treatment consists of chemotherapy with paclitaxel in combination with carboplatin after initial cytoreductive surgery. LÄS MER

4. 23. Selective Sorbents - Silica-immobilized affinity ligands and molecularly imprinted polymers

   Författare :Magnus Glad; Tillämpad biokemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular imprinting; HPLAC; composites; TRIM; Biokemi; Biochemistry; Metabolism; affinity chromatography;

   Sammanfattning : The development of selective sorbents for the separation of various molecules, preferentially biomolecules, is described in this work. Affinity ligands were immobilized on small silica particles and used in high-performance liquid affinity chromatography (HPLAC). LÄS MER

5. 24. The effect of malnutrition on saliva composition and caries development

   Författare :Ingegerd Johansson; Umeå universitet; []
   Nyckelord :starvation; protein-deficiency; antibacterial proteins; saliva; caries; infection;

   Sammanfattning : Starvation and protein deficiency increase susceptibility to infec­tions in general and affect the function of various types of cells individually. Saliva contains substances which offer protection to the oral tissues. Its composition and secretion rate may be important in preventing the development of disease, e.g. LÄS MER

7. 25. Host ligands and oral bacterial adhesion : studies on phosphorylated polypeptides and gp-340 in saliva and milk

   Författare :Liza Danielsson Niemi; Ingegerd Johansson; Pernilla Lif Holgersson; Jukka Meurman; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adhesion; statherin; gp-340; caseins; human milk; saliva; Streptococcus mutans; Actinomyces; Cariology; Cariologi; kariologi; Cariology;

   Sammanfattning : Infectious diseases e.g. gastric ulcer, caries and perodontitis, are caused by bacteria in a biofilm. Adhesion of bacteria to host ligands e. LÄS MER