Sökning: "gastroesophageal symptoms"

Visar resultat 6 - 10 av 31 avhandlingar innehållade orden gastroesophageal symptoms.

  1. 6. Gastroesophageal reflux and sleep problems

    Författare :Anna Lindam; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Gastroesophageal reflux disease (GERD) and sleep problems are common health problems in the Western world affecting up to 30% and 33% of the population respectively. GERD is associated with decreased quality of life, medication, increased use of health care facilities and increased risk of esophageal adenocarcinoma. LÄS MER

  3. 7. Pharmacometric Methods and Novel Models for Discrete Data

    Författare :Elodie L Plan; Mats O Karlsson; Laura Sargentini-Maier; Armel Stockis; Christian Laveille; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometrics; pharmacodynamics; disease progression; modelling; discrete data; count; ordered categorical; repeated time-to-event; RTTCE; RCEpT; NONMEM; FOCE; LAPLACE; SAEM; AGQ; pain scores; epilepsy seizures; gastroesophageal symptoms; statistical power; simulations; diagnostics; PHARMACY; FARMACI; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Sammanfattning : Pharmacodynamic processes and disease progression are increasingly characterized with pharmacometric models. However, modelling options for discrete-type responses remain limited, although these response variables are commonly encountered clinical endpoints. Types of data defined as discrete data are generally ordinal, e.g. LÄS MER

  4. 8. Hirschsprung´s Disease & Gastroesophageal Reflux. Aspects on Two Gastrointestinal Motility Disorders in Childhood

    Författare :Anna Gunnarsdottir; Neurogastroenterologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GERD; Gastroesophageal Reflux; Duhamel pull-through; TERPT; Quality of Life; ENS; CART; Hirschsprung´s Disease; GER; pH-monitoring; Wireless; BRAVO;

    Sammanfattning : Gastrointestinal motility disorders are common in childhood and in this thesis we look at two of them, i.e. Hirschsprung´s Disease (HD) and gastroesophageal reflux disease (GERD) in five different studies. LÄS MER

  5. 9. Proton pump inhibitors: indications and acid rebound

    Författare :Anna Niklasson; Göteborgs universitet; []
    Nyckelord :Proton pump inhibitors; indications; gastrointestinal symptoms; overuse; chronic obstructive pulmonary disease; acid rebound hypersecretion; gastroesophageal reflux disease;

    Sammanfattning : Proton pump inhibitors (PPIs) are nowadays the therapy of choice in the management of a variety of upper gastrointestinal (GI) conditions particularly gastroesophageal reflux disease (GERD). Previous studies indicate that patients commonly receive PPIs without clear indications. LÄS MER

  7. 10. Wireless esophageal PH monitoring. Clinical evaluation of a new technique

    Författare :Jörgen Wenner; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; orthopaedics; traumatology; Kirurgi; thresholds; specificity; sensitivity; diagnostic accuracy; adverse symptoms; wireless; pH monitoring; gastroesophageal reflux disease; ortopedi; traumatologi;

    Sammanfattning : Esophageal pH monitoring is important in the clinical management of patients with symptoms suggestive of gastroesophageal reflux disease (GERD), and in research aiming to clarify the mechanisms involved in the development of GERD complications. Catheter-based techniques for pH recording are uncomfortable, not well tolerated by all patients and cannot reliably measure acid exposure in the most distal esophagus the region most prone to reflux-induced complications. LÄS MER