Sökning: "endothelial function and risk factors"

Visar resultat 21 - 25 av 79 avhandlingar innehållade orden endothelial function and risk factors.

1. 21. Assessment of predicting blood flow and atherosclerosis in the aorta and renal arteries

   Författare :Alexander Fuchs; Lisa Prahl Wittberg; Örjan Smedby; Chunliang Wang; Anders Persson; Elazer Edelman; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Blodflödessimulering; Åderförkalkning; Väggskjuvspänning; Blodrehologiska modeller; Engineering Mechanics; Teknisk mekanik;

   Sammanfattning : Cardiovascular diseases (CVD) are the most common cause of death in large parts of the world. Atherosclerosis (AS) has a major part in most CVDs. AS is a slowly developingdisease which is dependent on multiple factors such as genetics and life style (food, smoking, and physical activities). LÄS MER

3. 22. Endogenous tissue-type plasminogen activator andendothelial function in vivo. A clinical perspective

   Författare :Thorarinn Gudnason; Göteborgs universitet; []
   Nyckelord :tissue-type plasminogen activator; endothelial function; age; vasodilation; chronic heart failure; coronary artery disease; local regulation; perfused-forearm model;

   Sammanfattning : Endogenous fibrinolysis is initiated by the glycoprotein tissue-type plasminogen activator (tPA), which is released from the vascular endothelium. Plasminogen activator inhibitor type 1 (PAI-1) is the main inhibitor of tPA. LÄS MER

4. 23. Endothelium-derived Vasoactive Factors and Leukocyte-derived Inflammatory Mediators. Studies in subjects with or at risk for vascular disease

   Författare :Anwaar M Ibrahim; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostacyclin.; Postmenopausal hormone replacement therapy; Nitric oxide; Endothelin; Diabetes mellitus; Cytokines; Cholesterol; Atherosclerosis; Cerebral ischemia; Cardiovascular system; Kardiovaskulära systemet;

   Sammanfattning : This study was undertaken to evaluate relationships between endothelial function (assessed as mediators of endothelium-derived vasoactive factors such as nitric oxide [NO], prostacyclin [PGI2] and endothelin [ET-1] ), and risk factors for atherosclerosis, as well as to study possible relationships between endothelial function and leukocyte activation (indicated by measurements of leukocyte-derived inflammatory mediators) in subjects with or at risk for atherosclerosis. In subjects with asymptomatic atherosclerosis we found inverse relationships between cyclic guanosine monophosphate (cGMP) in platelets (mediator of NO activity) and both serum total cholesterol and plasma ET-1 suggesting that NO-mediated vasodilation may be impaired in hypercholesterolemia and that maintenance of vascular tone is achieved by a balance between NO and ET-1. LÄS MER

5. 24. Cardiovascular function and biomarkers in women with preeclampsia

   Författare :Rangeen Rafik Hamad; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Preeclampsia; endothelial function; FMD; thrombin; microparticle; menstrual cycle; ventricular diastolic function; echocardiography; NT-pro-BNP; cystatin C; CRP; inflammation; hemostasis; Pentraxin 3; angiogenesis; pregnancy; follow-up;

   Sammanfattning : Background: Preeclampsia (PE) is a multisystem disorder peculiar to human pregnancy and characterized by the onset of hypertension and proteinuria after the 20th week of gestation. The pathophysiology of this disorder is still not clear. LÄS MER

7. 25. Studies on arterial endothelial function and intima-media thickness using ultrasound technique

   Författare :Morteza Rohani; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Ultrasound; atherosclerosis; flow mediated dilatation; endothelial function; carotid arteries; thoracic aorta; brachial artery; coronary artery disease; nicotine; snuff; prednisolone; rheumatoid arthritis;

   Sammanfattning : Background: The development of ultrasonographic arterial imaging, high-resolution B-mode ultrasonography, has created a technical basis for a new diagnostic approach to atherosclerotic disease by offering the possibility of accurate and reproducible quantification of the structural and functional changes in the arterial wall. Flow-mediated dilation (FMD) of the brachial artery and carotid intima-media thickness (IMT) have been shown to be good surrogate markers of atherosclerosis. LÄS MER