Sökning: "Cholesterol"

Visar resultat 1 - 5 av 577 avhandlingar innehållade ordet Cholesterol.

  1. 1. Cholesterol in T cells : homeostasis, plasma membrane organization and signaling

    Författare :Saleemulla Mahammad; Ingela Parmryd; Thomas Harder; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Plasma membrane; T cells; Cholesterol; Lipid rafts; Membrane organization; Cholesterol homeostasis; cholesteryl esters; Cell biology; Cellbiologi; cellbiologi; Cellbiology;

    Sammanfattning : The plasma membrane of eukaryotic cells contains cholesterol and glycosphingolipids enriched nanodomains known as lipid rafts; which are believed to exist in a liquid ordered (lo) state. Methyl-beta-cyclodextrin (MBCD) is used to deplete cellular cholesterol and a widespread assumption is that MBCD preferentially targets cholesterol in lipid rafts. LÄS MER

  3. 2. High Blood Cholesterol. Physician and Patient Perspectives

    Författare :Margareta Troein; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; qualitative method; practice guideline; pharmacist; life-style; information; hypercholesterolemia; health education; health belief; framework; family physician; family medicine; Cholesterol; counseling; screening; Social medicine; Socialmedicin; samhällsmedicin;

    Sammanfattning : Scientific evidence of the causal relationship between high blood cholesterol and risk for coronary heart disease prompted extensive professional and public interest in practical application in the 1980's. Among other things, national guidelines for lipid lowering were published in Sweden in 1988. Mass media covered the topic extensively. LÄS MER

  4. 3. Ion channels and electrical activity in vascular smooth muscle: Effects of calcium store depletion, cholesterol and cholesterol-lowering drugs

    Författare :Andreas Bergdahl; Kärlfysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; statins; endothelin; cholesterol; caveolae; smooth muscle; TRP; Ca2 channels; SOC;

    Sammanfattning : Smooth muscle cells (SMCs) in the vessel wall contract to regulate blood flow and pressure, a function essential for normal circulation through tissues. On the other hand, migration and proliferation of SMCs are important factors in vascular disease, such as atherosclerosis and restenosis following surgical dilatation. LÄS MER

  5. 4. Cholesterol-lowering and anti-atherogenic effects of oats in mice

    Författare :Kristina E Andersson; Cellulär biomekanik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cholesterol; Inflammation; Bile acids; Atherosclerosis; Oats; Beta-glucans;

    Sammanfattning : The cholesterol-lowering effect of oats is well established, but the crucial properties eliciting this effect need to be further investigated to optimize the use of oats as functional foods. Furthermore, there are almost no reports investigating the effect of oats on atherosclerosis development. LÄS MER

  7. 5. Plasma membrane order; the role of cholesterol and links to actin filaments

    Författare :Jelena Dinic; Ingela Parmryd; Gerrit van Meer; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Membrane Organization; Lipid rafts; Actin; Laurdan; di-4-ANEPPDHQ; Cholesterol; T cell signaling; Colocalization; Generalized Polarization; cellbiologi; Cellbiology;

    Sammanfattning : The connection between T cell activation, plasma membrane order and actin filament dynamics was the main focus of this study. Laurdan and di-4-ANEPPDHQ, membrane order sensing probes, were shown to report only on lipid packing rather than being influenced by the presence of membrane-inserted peptides justifying their use in membrane order studies. LÄS MER