Sökning: "FMD"

Visar resultat 1 - 5 av 28 avhandlingar innehållade ordet FMD.

  1. 1. Cardiovascular function and biomarkers in women with preeclampsia

    Författare :Rangeen Rafik Hamad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Preeclampsia; endothelial function; FMD; thrombin; microparticle; menstrual cycle; ventricular diastolic function; echocardiography; NT-pro-BNP; cystatin C; CRP; inflammation; hemostasis; Pentraxin 3; angiogenesis; pregnancy; follow-up;

    Sammanfattning : Background: Preeclampsia (PE) is a multisystem disorder peculiar to human pregnancy and characterized by the onset of hypertension and proteinuria after the 20th week of gestation. The pathophysiology of this disorder is still not clear. LÄS MER

  3. 2. Invasive treatment of renal artery stenosis - effects on blood pressure, medication, renal function and inflammatory biomarkers

    Författare :Alaa Al Hadad; Lund Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; Medicin människa och djur ; Medicine human and vertebrates ; inflammatory biomarkers; renal artery stenosis; Renovascular hypertension; percutaneous transluminal renal angioplasty; mean pressure gradient;

    Sammanfattning : Renal artery stenosis (RAS) causes hypertension, decreased glomerular filteration rate (GFR), and renal ischemia. RAS is progressive and causes 5-16% of all cases of renal failure. Prevalence of RAS in patients with hypertension is 1-5%. LÄS MER

  4. 3. On endothelial function in type 2 diabetic patients with coronary artery disease

    Författare :Thomas Nyström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Type 2 diabetes; endothelial dysfunction; insulin resistance; coronary artery disease; nitric oxide; glucagon-like peptide 1; exendin; tetrahydrobiopterin; inflammation; adiponectin; resistin; C-reactive protein; tumor necrosis factor a; interleukin-6;

    Sammanfattning : Patients with type 2 diabetes have a poor outcome suffering a myocardial infarction (MI). Endothelial dysfunction may play a role in this poor prognosis. In type 2 diabetes, endothelial dysfunction is a salient feature coexisting with obesity and insulin resistance and may be linked by the same pathophysiology, i.e. LÄS MER

  5. 4. Studies on arterial endothelial function and intima-media thickness using ultrasound technique

    Författare :Morteza Rohani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Ultrasound; atherosclerosis; flow mediated dilatation; endothelial function; carotid arteries; thoracic aorta; brachial artery; coronary artery disease; nicotine; snuff; prednisolone; rheumatoid arthritis;

    Sammanfattning : Background: The development of ultrasonographic arterial imaging, high-resolution B-mode ultrasonography, has created a technical basis for a new diagnostic approach to atherosclerotic disease by offering the possibility of accurate and reproducible quantification of the structural and functional changes in the arterial wall. Flow-mediated dilation (FMD) of the brachial artery and carotid intima-media thickness (IMT) have been shown to be good surrogate markers of atherosclerosis. LÄS MER

  7. 5. Clinical and Genetic Studies of Hearing Impairment

    Författare :Carina Frykholm; Ulla Friberg; Hans-Christian Larsen; Niklas Dahl; Marie-Louise Bondeson; Lisbeth Tranebjaerg; Uppsala universitet; []
    Nyckelord :Otorhinolaryngology; NF2; array-CGH; Meniere’s disease; PIK3C2G; X-linked; progressive; hearing impairment; Otorhinolaryngologi;

    Sammanfattning : Monogenic disorders offer a possibility for studies of genetic disturbances in hearing impairment—a knowledge which could be essential for development of future treatment options. In this thesis, the underlying genetic disturbances in neurofibromatosis 2 (NF2) and familial Meniere’s disease (FMD) were evaluated, and familial X-linked hearing impairment was described from a clinical point of view. LÄS MER