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11. Membrane Induced Structure in Transmembrane Signaling Proteins and Peptides : Peptide–Lipid Interactions Studied by Spectroscopic Methods
Sammanfattning : Biological membranes, defining the boundary of cells and eukaryotic organelles, are mainly composed of lipids and membrane proteins. Interactions between these lipids and proteins are needed to preserve the tight seal of the membrane, but also to induce structure for proper function in many membrane proteins. LÄS MER
12. Domain engineering in KTiOPO4
Sammanfattning : Ferroelectric crystals are commonly used in nonlinear optics for frequency conversion of laser radiation. The quasi-phase matching (QPM) approach uses a periodically modulated nonlinearity that can be achieved by periodically inverting domains in ferroelectric crystals and allows versatile and efficient frequency conversion in the whole transparency region of the material. LÄS MER
13. The relationship between orthology, protein domain architecture and protein function
Sammanfattning : Lacking experimental data, protein function is often predicted from evolutionary and protein structure theory. Under the 'domain grammar' hypothesis the function of a protein follows from the domains it encodes. LÄS MER
14. Anomaly detection in the surveillance domain
Sammanfattning : In the post September 11 era, the demand for security has increased in virtually all parts of the society. The need for increased security originates from the emergence of new threats which differ from the traditional ones in such a way that they cannot be easily defined and are sometimes unknown or hidden in the “noise” of daily life. LÄS MER
15. Domain swapping as a molecular mechanism in amyloidosis
Sammanfattning : Amyloidosis is a group of diseases characterized by a change in protein conformation resulting in aggregation and tissue deposition of amyloid fibrils. One variant of cystatin C, L68Q cystatin C, is highly amyloidogenic and persons carrying the corresponding gene suffer from massive cerebral amyloidosis leading to brain hemorrhage and death. LÄS MER