Sökning: "protein domains"

Visar resultat 1 - 5 av 549 avhandlingar innehållade orden protein domains.

1. 1. NMR Studies of Bacterial Albumin-Binding Modules

   Författare :Maria U Johansson; Biofysikalisk kemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Fysikalisk kemi; Biotechnology; Bioteknik; Proteins; enzymology; Proteiner; enzymologi; Physical chemistry; three-helix bundle; protein structure; protein PAB; protein-protein interactions; protein G; protein dynamics; NMR; module shuffling; GA module; evolution; albumin-binding; bacterial surface proteins;

   Sammanfattning : Peptostreptococcus magnus and group C/G streptococci are Gram-positive cocci that are part of the normal flora and reside in more or less the same locations in the host. Protein G of group C/G streptococci was originally described as binding IgGFc of several species and later shown to also bind human serum albumin and albumins from various animal species. LÄS MER

3. 2. Protein modularity : Structure and interactions by NMR and SPR

   Författare :Amélie Wallenhammar; Maria Sunnerhagen; Björn Wallner; Lotta Tollstoy-Tegler; Helena Berglund; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Protein degradation is a fundamental cornerstone of regulation of protein levels in the human body. For proper function, numerous molecular processes rely on fine-tuned communication through specific interactions between proteins. LÄS MER

4. 3. Recombinant subunit vaccines : protein immunogens

   Författare :Sissela Liljeqvist; KTH; []
   Nyckelord :;

   Sammanfattning : Recombinant techniques provide valuable tools for thedevelopment of modern subunit vaccines. In this thesisdifferent systems for production of recombinant subunitvaccines are presented. The strategies investigated includeprotein immunogens, live bacterial vectors and nucleicacids. LÄS MER

5. 4. Engineering of small IgG binding domains for antibody labelling and purification

   Författare :Sara Kanje; Sophia Hober; Cecília Roque; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Antibody; labelling; purification; Protein G; Protein A; protein engineering; protein design; combinatorial selection; Bioteknologi; Biotechnology;

   Sammanfattning : In protein engineering, rational design and selection from combinatorial libraries are methods used to develop proteins with new or improved features. A very important protein for the biological sciences is the antibody that is used as a detecting agent in numerous laboratory assays. LÄS MER

7. 5. The relationship between orthology, protein domain architecture and protein function

   Författare :Kristoffer Forslund; Erik Sonnhammer; Cristina Al-Khalili Szigyarto; Sarah Teichmann; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; homology; orthology; paralogy; gene duplications; protein function prediction; low-complexity regions; protein domains; domain architecture evolution; introns; intron position conservation; orthology conjecture; domain grammar hypothesis; biokemi; inriktning teoretisk kemi; Biochemistry with Emphasis on Theoretical Chemistry;

   Sammanfattning : Lacking experimental data, protein function is often predicted from evolutionary and protein structure theory. Under the 'domain grammar' hypothesis the function of a protein follows from the domains it encodes. LÄS MER