Sökning: "Lena Mäler"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden Lena Mäler.

1. 1. NMR relaxation studies of molecular dynamics and nuclear spin interactions in solution

   Författare :Lena Mäler; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molekylbindning; Elektronspinmätning;

   Sammanfattning : .... LÄS MER

3. 2. Improved Methods for Characterization of Protein Dynamics by NMR spectroscopy and Studies of the EphB2 Kinase Domain

   Författare :Alexandra Ahlner; Patrik Lundström; Bengt-Harald Jonsson; Lena Mäler; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Proteins are essential for all known forms of life and in many lethal diseases protein failure is the cause of the disease. To understand proteins and the processes they are involved in, it is valuable to know their structures as well as their dynamics and interactions. LÄS MER

4. 3. The Application of isotropic bicelles as model membranes

   Författare :August Andersson; Lena Mäler; G Arthur III Palmer; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bicelle; membrane; peptide; spectroscopy; NMR; Molecular biophysics; Molekylär biofysik;

   Sammanfattning : Isotropic bicelles are disc-shaped aggregates of lipids and detergents, and are suitable model systems for high-resolution NMR studies of membrane-interacting peptides. In this thesis the structures for the two peptides motilin and transportan were determined by homonuclear 1H methods in the presence of bicelles, and the structure of the bovine prion protein peptide (bPrPp) was solved in the presence of DHPC micelles. LÄS MER

5. 4. Protein Structure and Interaction in Health and Disease

   Författare :Cecilia Andrésen; Maria Sunnerhagen; Patrik Lundström; Lena Mäler; Linköpings universitet; []
   Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

   Sammanfattning : This thesis focuses on protein structure, dynamics and interaction and their relation to human disease. In particular, the biophysical and structural properties of both well-ordered and partially disordered proteins are studied using a range of biophysical techniques such as circular dichroism spectroscopy, fluorescence spectroscopy, mass spectrometry and nuclear magnetic resonance spectroscopy. LÄS MER

7. 5. Structure and Dynamics of Membrane Associated Peptides

   Författare :Henrik Biverståhl; Lena Mäler; Charles R. Sanders; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biophysics; Biofysik; Biophysics; biofysik;

   Sammanfattning : The peptide-membrane interaction is a key element for many biological functions, from cell signaling to cell internalization. In this thesis the peptide-membrane interaction of six different peptides have been studied with respect to their structure, membrane location and dynamics with spectroscopic methods. LÄS MER