Sökning: "HAMP domain"

Hittade 4 avhandlingar innehållade orden HAMP domain.

  1. 1. Membrane Induced Structure in Transmembrane Signaling Proteins and Peptides : Peptide–Lipid Interactions Studied by Spectroscopic Methods

    Författare :Sofia E. Unnerståle; Lena Mäler; Jason Schnell; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; peptide-lipid interaction; paddle domain; voltage gating; voltage sensor domain; micelle; phospholipid bicelle; solution structure; HAMP domain; nuclear magnetic resonance spectroscopy; circular dichroism spectroscopy; nonspecific interaction; Biophysics; biofysik;

    Sammanfattning : Biological membranes, defining the boundary of cells and eukaryotic organelles, are mainly composed of lipids and membrane proteins. Interactions between these lipids and proteins are needed to preserve the tight seal of the membrane, but also to induce structure for proper function in many membrane proteins. LÄS MER

  3. 2. NMR Investigations of Peptide-Membrane Interactions, Modulation of Peptide-Lipid Interaction as a Switch in Signaling across the Lipid Bilayer

    Författare :Sofia Unnerståle; Lena Mäler; Göran Widmalm; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; peptide-lipid interaction; membrane mimetic; NMR; biophysics; Molecular biophysics; Molekylär biofysik; biofysik; Biophysics;

    Sammanfattning : The complexity of multi cellular organisms demands systems that facilitate communicationbetween cells. The neurons in our brains for instance are specialized in this cell-cellcommunication. LÄS MER

  4. 3. Bacterial virulence and adaptation mediated by two-component system signalling

    Författare :Henrik Tomenius; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Virulence; atomic force microscopy; biofilm; adaptation; two-component system; signal transduction; gene regulation; phosphorylation; BarA; UvrY;

    Sammanfattning : One of the most fundamental ways of signal perception and propagation is mediated by the bacterial two-component system (TCS). These types of systems mediate bacterial adaptation that may cause disease in a host due to expression of virulence factors. LÄS MER

  5. 4. Time-resolved X-ray diffraction and solution scattering studies of Sensory Rhodopsin II in isolation and in complex with its transducer

    Författare :Giorgia Ortolani; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; light-activated membrane protein; microbial Rhodopsins; Sensory rhodopsin II; SRII; SRII:HtrII; transducer; SSX; XSS; time-resolved;

    Sammanfattning : Light is an important source of energy for many living organisms. Many life forms have therefore evolved cellular receptors that are able to sense light and thereby optimise conditions for photosynthesis and pho- totrophy. LÄS MER