Sökning: "differential RNA expression"
Visar resultat 6 - 10 av 76 avhandlingar innehållade orden differential RNA expression.
6. Genomic and transcriptomic investigation of reproductive incompatibility in Drosophila
Sammanfattning : Both nuclear and cytoplasmic elements can contribute to the emergence of reproductive incompatibilities that influence evolution and speciation. In the projects that compose this thesis, we use genomics and transcriptomics to study some of those elements in Drosophila. LÄS MER
7. The diverse functions of the ADAR enzymes : Editing and editing-independent effects on gene expression
Sammanfattning : The adenosine deaminase acting on RNA (ADAR) family of enzymes consists of three members (ADAR1-3). These enzymes are responsible for the deamination of adenosine into inosine in double-stranded RNA, one of the most common RNA modifications in mammals. LÄS MER
8. Aspects of Gene Expression Profiling in Disease and Health
Sammanfattning : The aim of this thesis is to in various ways explore protein expression in human normal tissue and in cancer and to apply that knowledge in biomarker discovery.In Paper I the prognostic significance of RNA-binding motif protein 3 (RBM3) is explored in malignant melanoma. LÄS MER
9. miRNA and Asymmetric siRNA : Small RNAs with Large Effects on Bone Metabolism
Sammanfattning : RNA interference (RNAi) is a post-transcriptional gene silencing process elicited by double-stranded RNA, such as micro-RNA (miRNA) and small interfering RNA (siRNA). They are 18-25 nucleotide long, small non-coding RNAs acting as critical regulators in eukaryotic genome expression. LÄS MER
10. Epigenetic and Gene Expression Signatures in Systemic Inflammatory Autoimmune Diseases
Sammanfattning : Autoimmune diseases are clinical manifestations of a loss-of-tolerance of the immune system against the body’s own substances and healthy tissues. Primary Sjögren’s syndrome (pSS) and systemic lupus erythematosus (SLE) are two chronic inflammatory autoimmune diseases characterized by autoantibody production and an activated type I interferon system. LÄS MER