Sökning: "danger signal"
Visar resultat 11 - 15 av 18 avhandlingar innehållade orden danger signal.
11. Human dendritic cells in blood and airways during respiratory viral infection
Sammanfattning : The air we inhale contains oxygen necessary for life, but also potentially harmful microorganisms, toxins and allergens. This presents an important immunological dilemma: how can our lungs quickly and selectively eliminate harmful agents without inflicting damage on the delicate tissues of the lungs? We have thus evolved a network of cells involved in immune surveillance, made up of dendritic cells (DCs), monocytes and macrophages. LÄS MER
12. RsbX and stress response in Listeria monocytogenes
Sammanfattning : Listeria monocytogenes is a ubiquitous foodborne Gram-positive bacterium. Despite being mainly a soil bacterium, it can reach the food processing environment and contaminate food destined for human consumption, causing outbreaks. LÄS MER
13. Arthritogenecity of RNA and its degradation products
Sammanfattning : Viral infections often lead to arthralgias and overt arthritic states. Expression of double stranded RNA (dsRNA) is a common feature of all viruses during their replication and it has been suggested that it is able to induce production of pro-inflammatory cytokines, e.g., interferon-alpha (IFN-alpha). LÄS MER
14. Innate immune responses to Mycobacterium tuberculosis infection : How extracellular traps and trained immunity can restrict bacterial growth
Sammanfattning : Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis, and the cause of 1.5 million deaths in 2018. During a pulmonary TB infection, the bacterium reaches the lungs and is phagocytosed by cells of the innate immune system, primarily macrophages. LÄS MER
15. Characterization of host and microbe interactions affecting adherence, clearance and systemic spread of S. pneumoniae
Sammanfattning : Streptococcus pneumoniae (the pneumococcus) mainly gives rise to diseases of the respiratory tract, such as pneumonia, acute otitis media and sinusitis, but it also causes severe invasive diseases, such as meningitis and sepsis. The pneumococcus accounts for approximately two million deaths world-wide every year, the majority of which are children in developing countries. LÄS MER