Sökning: "cyclin"
Visar resultat 6 - 10 av 187 avhandlingar innehållade ordet cyclin.
6. Immunofluorescence studies on the cell cycle expression of cyclin A and cyclin E
Sammanfattning : Cell cycle progression is tightly regulated in normal eucaryotic cells. Cancer is caused by the transformation of cells, and is always associated with defects in the cell cycle regulatory machinery. LÄS MER
7. Cell Cycle Regulation in Human Renal Cell Carcinoma
Sammanfattning : ABSTRACTCell cycle regulation in human renal cell carcinomaYlva Hedberg, Departments of Medical Biosciences, Pathology, and Surgical andPerioperative Sciences, Urology Andrology, Umeå University, SwedenDeregulated growth control is a hallmark of neoplasia potentially caused by aberrant expression of cell cycle regulatory proteins. The importance of such aberrations in human renal cell carcinoma (RCC) has not been fully clarified. LÄS MER
8. The Prognostic and Treatment Predictive Value of Proliferation and TIMP-1 in Breast Cancer
Sammanfattning : Breast cancer is the most common tumour form and the second leading cause of death in solid tumours in women in the Western world. Despite improvements in the treatment, a considerable number of patients will relapse and die from their breast cancer. LÄS MER
9. Functional studies in yeast of cyclin C and the RNA polymerase II Mediator complex
Sammanfattning : Cyclin C belongs to a group of cyclins that are not cell cycle-regulated. It was first cloned from Drosophila and rat, but its role was not understood until the yeast cyclin C homologue Srb 11 was identified in several genetic screens for transcriptional repressors and subsequently was shown to be associated with the RNA polymerase II Mediator complex. LÄS MER
10. G1-phase cyclin expression in neoplastic B cells
Sammanfattning : By virtue of the role of G1-phase cyclin proteins as regulators of differentiation, proliferation, and apoptosis, their improper expression can lead to altered cellular homeostasis and tumor formation. Cyclins provide the regulatory partner for cyclin-cdk complexes whose enzymatic activity drives cell cycle progression. LÄS MER