Sökning: "damage accumulation"

Visar resultat 1 - 5 av 164 avhandlingar innehållade orden damage accumulation.

  1. 1. Radiation response in human cells DNA damage formation, repair and signaling

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ann-Sofie Gustafsson; Uppsala universitet.; [2015]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DNA damage; DNA repair; DSB; NHEJ; DNA-PK; ionizing radiation; heat-labile sites; Biomedical Radiation Science; Biomedicinsk strålningsvetenskap;

    Sammanfattning : Ionizing radiation induces a range of different DNA lesions. In terms of mutation frequency and mammalian cell survival, the most critical of these lesions is the DNA double-strand break (DSB). DSB left unrepaired or mis-repaired may result in chromosomal aberrations that can lead to permanent genetic changes or cell death. LÄS MER

  2. 2. Damage accumulation and stiffness degradation in composite laminates

    Detta är en avhandling från Luleå : Luleå tekniska universitet

    Författare :Roberts Joffe; Luleå tekniska universitet.; [1999]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Polymeric Composite Materials; Polymera konstruktionsmaterial;

    Sammanfattning : In the presented thesis analytical modeling of elastic properties degradation and modeling of damage evolution in composite laminates is performed. Transverse cracking initiation on a fiber/matrix level is briefly studied by testing model composites and cross-ply laminates. LÄS MER

  3. 3. Damage Segregation and Cellular Rejuvenation in Saccharomyces cerevisiae

    Detta är en avhandling från Göteborg : University of Gothenburg

    Författare :Sandra Malmgren Hill; Göteborgs universitet.; Gothenburg University.; [2015]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Aging; protein damage; quality control; metacaspase; aggregates; segregation; vacuole;

    Sammanfattning : The process of aging is defined as a time-dependent decline in cellular functionality, and aging is thought to have evolved as organisms were optimized for reproduction, at the cost of an imperfect repair and maintenance system. As a consequence, different kinds of dysfunctional components and damage accumulate over time. LÄS MER

  4. 4. Development of a Morphology-based Analysis Framework for Asphalt Pavements

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Ibrahim Onifade; KTH.; [2015]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Morphology; damage; X-ray computed tomography; top-down cracking; fracture; Morfologi; skador; röntgendatortomografi; ’top-down’sprickbildning; fraktur; Civil and Architectural Engineering; Byggvetenskap; Materials Science and Engineering; Teknisk materialvetenskap;

    Sammanfattning : The morphology of asphalt mixtures plays a vital role in their properties and behaviour. The work in this thesis is aimed at developing a fundamental understanding of the effect of the asphalt morphology on the strength properties and deformation mechanisms for development of morphology-based analysis framework for long-term response prediction. LÄS MER

  5. 5. Risk from radionuclides: a frog's perspective Accumulation of 137Cs in a riparian wetland, radiation doses, and effects on frogs and toads after low-dose rate exposure

    Detta är en avhandling från Stockholm : Systemekologiska institutionen

    Författare :Karolina Stark; Stockholms universitet.; [2006]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; dose model; mass balance budget; overbank sedimentation; amphibian; phantom; thermoluminescence chip; radiosensitivity; DNA damage; NATURAL SCIENCES Biology; NATURVETENSKAP Biologi;

    Sammanfattning : Threats from man-made radionuclides include waste issues, increasing number of power plants, underground bomb testing, nuclear weapons, and “dirty bombs”. Until recently the ionizing radiation protection system focused on protecting humans with an implied protection of biota. LÄS MER