Sökning: "cross coupling"

Visar resultat 11 - 15 av 176 avhandlingar innehållade orden cross coupling.

  1. 11. Thiol−ene Coupling of Renewable Monomers : at the forefront of bio-based polymeric materials

    Författare :Mauro Claudino; Mats K. G. Johansson; Mats Jonsson; Anna Wistrand; Sven Göthe; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Thiol-ene chemistry; monounsaturated fatty-acids; renewable resources; cis trans-isomerization; photopolymerization; networks; polyesters; thermal viscoelastic properties; thin-films; unsaturated macro lactones; coatings;

    Sammanfattning : Plant derived oils bear intrinsic double-bond functionality that can be utilized directly for the thiol–ene reaction. Although terminal unsaturations are far more reactive than internal ones, studies on the reversible addition of thiyl radicals to 1,2-disubstituted alkenes show that this is an important reaction. LÄS MER

  3. 12. Design and Synthesis of Novel HIV-1 Protease Inhibitors Comprising a Tertiary Alcohol in the Transition-State Mimic

    Författare :Jenny Ekegren; Anders Hallberg; Daniel Rich; Uppsala universitet; []
    Nyckelord :Chemistry; HIV AIDS; HIV-1 protease inhibitor; transition-state mimic; tertiary alcohol; palladium; cross-coupling; aminocarbonylation; microwave; molybdenum hexacarbonyl; Kemi;

    Sammanfattning : HIV-1 protease inhibitors are important in the most frequently used regimen for the treatment of HIV/AIDS, the highly active antiretroviral therapy (HAART). For patients with access to this treatment, an HIV infection is no longer lethal, but rather a manageable, chronic infection. LÄS MER

  4. 13. Enantioenriched Cyanohydrins and Acetoxyphosphonates – Synthesis and Applications

    Författare :Robin Hertzberg; Christina Moberg; Frank Glorius; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; asymmetric synthesis; cyanohydrins; acetoxyphosphonates; biocatalyst; titanium catalyst; minor enantiomer recycling; cross-coupling; amino alcohols; Kemi; Chemistry;

    Sammanfattning : In this thesis, the synthesis of enantioenriched compounds using novel methodologies that employ metal- and biocatalysis is described.In the first part, the synthesis of enantioenriched cyanohydrins, which are highly versatile synthetic intermediates, is described. LÄS MER

  5. 14. MECHANISTIC INVESTIGATIONS OF TRANSITION METAL CATALYZED REACTIONS

    Författare :Jonatan Kleimark; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; alkene insertion; allylic alkylation; catalysis; cross coupling; density funtional theory; free energy surface; iron; kinetic investigation; Mizoroki-Heck reaction; nickel; palladium; reaction mechanism; sulfinylation; transition metal;

    Sammanfattning : Transition metal catalyzed reactions have had a large impact on the human progress for the last century. Several extremely important areas, such as the agricultural industry and the plastic industry, have benefited from this development. LÄS MER

  7. 15. Transition Metal Mediated Transformations of Carboranes

    Författare :Ludvig Eriksson; Kalman Szabo; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; carborane; isoquinoline; PK11195; peripheral bensodiazepine receptor; Cu I Iodide; iodinated carborane; palladium; isotopic exchange; Herrmann’s Catalyst; Heck reaction; Suzuki-Miyaura reaction; cross coupling; arylation; olefination; 125-iodine; radiolabelling; carboraneboronic ester; BNCT; 2-iodo-; Kemi; Chemistry; Kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis describes the use of copper and palladium to mediate transformations of carboranes, especially p-carborane.1-(1-p-carboranyl)-N-methyl-N-(2-butyl)-3-isoquinolinecarboxamide, a carborane containing analogue of the peripheral benzodiazepine receptor (PBR) ligand PK11195, has been synthesised. LÄS MER