Sökning: "isoquinoline"
Hittade 5 avhandlingar innehållade ordet isoquinoline.
1. Transition Metal Mediated Transformations of Carboranes
Sammanfattning : This thesis describes the use of copper and palladium to mediate transformations of carboranes, especially p-carborane.1-(1-p-carboranyl)-N-methyl-N-(2-butyl)-3-isoquinolinecarboxamide, a carborane containing analogue of the peripheral benzodiazepine receptor (PBR) ligand PK11195, has been synthesised. LÄS MER
2. Synthesis of biomolecules for nuclide therapy : Studies on amino acids, nucleosides and isoquinolines
Sammanfattning : Nuclide therapy for cancer is based on the selective delivery of nuclide bearing compounds to tumour cells. Radionuclides, such as 125I, may be used, as well as stable isotopes, such as 10B, which is activated on site by an external neutron source. LÄS MER
3. [11C]Carbon Monoxide and Aryl Triflates in Palladium-Mediated Carbonylation Reactions : Synthetic approaches to [11C]Carbonyl Compounds and [11C]Amines
Sammanfattning : The usefulness of low concentrations (typically 10 to 100 µM) of [11C]carbon monoxide and aryl triflates as substrates in 11C-carbonylation using different nucleophiles in the presence of lithium bromide was investigated. The reactions were performed in a micro autoclave of 200 µL volume and catalysed (mediated) by palladium(0). LÄS MER
4. Radiohalogenation of biomolecules : An experimental study on radiohalogen preparation, precursor synthesis, radiolabeling and biodistribution
Sammanfattning : Radiohalogens are widely used in nuclear medicine, both as tool for diagnostic in vivo imaging and inradionuclide therapy. This study deals with the use of radiohalogens; separation, precursor synthesis, labeling and biological behavior. LÄS MER
5. Elicitor-induced formation of secondary products in plant cell cultures. Production of benzophenanthridine alkaloids in Eschscholtzia californica Cham. and hydroxycinnamic acid tyramides in Nicotiana glutinosa L
Sammanfattning : Biotic and abiotic elicitors induce biosynthesis of secondary metabolites (phytoalexins) as a defense against pathogenic organisms in plants. The use of cell suspension cultures in combination with elicitors offer excellent experimental model systems for studies on various elicitor-induced responses of plant tissues. LÄS MER