Sökning: "cerebral microdialysis"

Visar resultat 21 - 25 av 27 avhandlingar innehållade orden cerebral microdialysis.

1. 21. Factors related to outcome in patients with traumatic brain injury : with special reference to analysis with machine learning methods

   Författare :David Nelson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Traumatic brain injury; Glasgow coma scale; Glasgow outcome scale; microdialysis; computed tomography; hematologic tests; machine learning;

   Sammanfattning : Traumatic brain injury (TBI) is a leading cause of death in trauma. Neurointensive care (NICU) units have emerged to optimize treatments of the injured brain. The main objective is to identify and avoid conditions that lead to further insult and potential cell death. LÄS MER

3. 22. Aspects on Mechanisms, Treatment and Outcome in Severe Traumatic Brain Injury

   Författare :Teodor Svedung Wettervik; Anders Lewén; Per Enblad; Elham Rostami; Lars-Owe Koskinen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoregulation; clinical outcome; energy metabolism; multimodality monitoring; neurointensive-care; traumatic brain injury; Neurokirurgi; Neurosurgery;

   Sammanfattning : Traumatic brain injury (TBI) is a leading cause for mortality and morbidity worldwide. The primary injury has great impact on patient outcome and cannot be cured, but attentive neurointensive care (NIC) may reduce detrimental secondary brain injuries and is the focus of this thesis. LÄS MER

4. 23. Pathophysiology of intrauterine asphyxia

   Författare :Anna-Karin Welin; Göteborgs universitet; []
   Nyckelord :asphyxia; ECG; endotoxemia; fetal sheep; inflammation; melatonin; periventricular leukomalacia; preterm;

   Sammanfattning : Background: The premature infant is at increased risk of cerebral white matter damage, oftenreferred to as periventricular leucomalacia, PVL, which is associated with later developmentof cerebral palsy and cognitive impairment. The etiology of PVL remains unclear, but ischemia-reperfusion followed by generation of free radicals and intrauterine infections havebeen suggested to play an important role. LÄS MER

5. 24. On biomarkers in traumatic brain injury

   Författare :Eric Thelin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Traumatic brain injury (TBI) is a common cause of death and disability. Unfortunately, TBI patients will be affected by secondary insults, such as hypoxia and increased intracranial pressure, which may lead to secondary brain injuries. LÄS MER

7. 25. Surgically Treated Intracerebral Haemorrhage : Pathophysiology and Clinical Aspects

   Författare :Lovisa Tobieson; Niklas Marklund; Bijar Ghafouri; Sandro Rossitti; Peter Zsigmond; Jan Hillman; Mikael Svensson; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Mortality and morbidity of intracerebral haemorrhage (ICH) is excessively high, and the case fatality rate has not improved in the last decades. Although surgery for ICH can be life-saving, no positive effect on functional outcome has been found in large cohorts of ICH patients. LÄS MER