Sökning: "cellular aging"
Visar resultat 11 - 15 av 67 avhandlingar innehållade orden cellular aging.
11. Telomeres and the brain : an investigation into the relationships of leukocyte telomere length with functional and structural attributes of the brain
Sammanfattning : Telomeres are the outermost parts of linear chromosomes. They consist of tandemly repeated non-coding short nucleotide sequences (TTAGGG in all vertebrates), in humans spanning over the last 2 to 15 kilobase pairs of the chromosome. Due to the end-replication problem, telomeres shorten with each cellular division. LÄS MER
12. Caulobacter crescentus folding machines at the interface of inheritance, cell division, and energy metabolism
Sammanfattning : All living cells must perform essential biological processes while monitoring and responding to environmental cues. Bacteria are accessible experimental systems in which to study the function of conserved central processes. LÄS MER
13. The Role of Hepatic Leukemia Factor in Hematopoiesis
Sammanfattning : The development of therapeutic methods based on stem cells (e.g. cell therapy, activating regeneration and organ transplantation), known as regenerative medicine, is still a novel area in the field of life sciences. LÄS MER
14. Early Blood Cell Formation "in sickness and health, ´till death do us part"
Sammanfattning : Hematopoietic stem cells (HSC), the ancestors of all blood cells, have the ability to give rise to mature effector cells through a series of developmental steps. This is a tightly regulated, though a highly dynamic process: on the one hand, dysregulation in steady-state could lead to under- or overgrowth of certain blood cell lineages, whereas, on the other hand, demands for certain mature blood cells can change dramatically in cases like bleeding and infections. LÄS MER
15. Free radicals in cellular pathology : Mechanisms behind lipofucin formation in cultured myocardial cells
Sammanfattning : Lipofuscin, or age pigment, may be defined as a yellowish-brown,autofluorescent, protein and lipid containing pigment that accumulates inthe lysosomal vacuome of a variety of post-mitotic cell types in man andanimals during aging. Lipofuscin is the end product of peroxidation,fragmentation and polymerization of proteins and lipids. LÄS MER